• Log InLog In
  • Register
Liquid`
Team Liquid Liquipedia
EDT 11:12
CEST 17:12
KST 00:12
  • Home
  • Forum
  • Calendar
  • Streams
  • Liquipedia
  • Features
  • Store
  • EPT
  • TL+
  • StarCraft 2
  • Brood War
  • Smash
  • Heroes
  • Counter-Strike
  • Overwatch
  • Liquibet
  • Fantasy StarCraft
  • TLPD
  • StarCraft 2
  • Brood War
  • Blogs
Forum Sidebar
Events/Features
News
Featured News
Code S Season 1 (2026) - RO4 & Finals Preview5[ASL21] Ro4 Preview: On Course12Code S Season 1 - RO8 Preview7[ASL21] Ro8 Preview Pt2: Progenitors8Code S Season 1 - RO12 Group A: Rogue, Percival, Solar, Zoun13
Community News
Code S Season 1 (2026) - RO8 Results2Weekly Cups (May 4-10): Clem, MaxPax, herO win1Maestros of The Game 2 announcement and schedule !16Weekly Cups (April 27-May 4): Clem takes triple0RSL Revival: Season 5 - Qualifiers and Main Event12
StarCraft 2
General
Code S Season 1 (2026) - RO4 & Finals Preview Team Liquid Map Contest #22 - The Finalists Code S Season 1 (2026) - RO8 Results Code S Season 1 (2026) - RO12 Results MaNa leaves Team Liquid
Tourneys
Maestros of The Game 2 announcement and schedule ! GSL Code S Season 1 (2026) Sparkling Tuna Cup - Weekly Open Tournament KSL Week 89 2026 GSL Season 2 Qualifiers
Strategy
Custom Maps
[D]RTS in all its shapes and glory <3 [A] Nemrods 1/4 players
External Content
The PondCast: SC2 News & Results Mutation # 526 Rubber and Glue Mutation # 525 Wheel of Misfortune Mutation # 524 Death and Taxes
Brood War
General
25 Years Since Brood War Patch 1.08 vespene.gg — BW replays in browser BW General Discussion Data needed BGH Auto Balance -> http://bghmmr.eu/
Tourneys
[ASL21] Semifinals B [BSL22] RO8 Bracket Stage + Another TieBreaker [ASL21] Ro8 Day 4 Escore Tournament StarCraft Season 2
Strategy
Muta micro map competition Fighting Spirit mining rates [G] Hydra ZvZ: An Introduction Simple Questions, Simple Answers
Other Games
General Games
Warcraft III: The Frozen Throne ZeroSpace Megathread Stormgate/Frost Giant Megathread War of Dots, 2026 minimalst RTS Nintendo Switch Thread
Dota 2
The Story of Wings Gaming
League of Legends
Heroes of the Storm
Simple Questions, Simple Answers Heroes of the Storm 2.0
Hearthstone
Deck construction bug Heroes of StarCraft mini-set
TL Mafia
Vanilla Mini Mafia Mafia Game Mode Feedback/Ideas TL Mafia Community Thread Five o'clock TL Mafia
Community
General
US Politics Mega-thread European Politico-economics QA Mega-thread YouTube Thread Russo-Ukrainian War Thread UK Politics Mega-thread
Fan Clubs
The herO Fan Club!
Media & Entertainment
[Manga] One Piece Anime Discussion Thread [Req][Books] Good Fantasy/SciFi books
Sports
2024 - 2026 Football Thread McBoner: A hockey love story Formula 1 Discussion
World Cup 2022
Tech Support
streaming software Strange computer issues (software) [G] How to Block Livestream Ads
TL Community
The Automated Ban List
Blogs
Why RTS gamers make better f…
gosubay
How EEG Data Can Predict Gam…
TrAiDoS
ramps on octagon
StaticNine
Customize Sidebar...

Website Feedback

Closed Threads



Active: 1975 users

Ask and answer stupid questions here! - Page 588

Forum Index > General Forum
Post a Reply
Prev 1 586 587 588 589 590 783 Next
riotjune
Profile Blog Joined January 2008
United States3394 Posts
Last Edited: 2017-02-10 08:12:44
February 10 2017 07:54 GMT
#11741
On February 10 2017 16:02 FiWiFaKi wrote:
Show nested quote +
On February 10 2017 13:19 riotjune wrote:
Are there cigarettes that smell like skunk? Wonder if neighbors are smoking a specific brand or doing recreationals.


I've had skunks in my backyard before, so it's not impossible.

Nothing drug related that I can think of off the top of my head that smells like skunk.

On February 10 2017 16:40 Acrofales wrote:
Are you talking about skunk
+ Show Spoiler +
[image loading]


Or skunk?
+ Show Spoiler +
[image loading]

Do the animal and plant smell the same (sulfur-containing thiols)?

I have the windows closed and I don't think skunks would be running around this time of the year with the snow and all. It is known cigarette odors waft up into my apartment, and when the occasional skunk odor comes around I can only conclude the people below are doing skunk weed or something (or keeping a skunk around as a pet )
xM(Z
Profile Joined November 2006
Romania5299 Posts
February 10 2017 08:24 GMT
#11742
On February 10 2017 09:22 Cascade wrote:
Show nested quote +
On February 09 2017 21:39 xM(Z wrote:
On February 09 2017 18:30 Cascade wrote:
On February 09 2017 17:33 xM(Z wrote:
On February 09 2017 17:09 Cascade wrote:
On February 09 2017 16:51 xM(Z wrote:
On February 09 2017 15:07 Cascade wrote:
On February 09 2017 03:38 xM(Z wrote:
epigenetics, depression, sperm, nature, microRNA, offsprings ... go!.

I'm pretty sure you tried that already, or something very similar. Or was that someone else? I think it was you...
wasn't me; what came out of it?.

I was thinking of your GMO antics + Show Spoiler +
On January 12 2017 15:23 Cascade wrote:
Show nested quote +
On January 12 2017 04:21 xM(Z wrote:
you mixed up my phrasing - protein signaling with protein digestion.
- protein signaling based on gene mutation(no one knows why it mutates but environmental as well as hereditary reasons are quoted) causes Parkinson;
- protein digestion - irritable bowel syndrome, autoimmune disorders and others

pepsin stops digesting nucleic acids(DNA) at ~8ph; with all them hipsters on pure alkaline diets, nothing is guaranteed.

I'm trying to understand here... Are you afraid that:

1) GMO plants will happen to have DNA that cause Parkinsons in humans, but the wild type plant doesn't.
2) We eat the GMOs, and the DNA somehow doesn't get digested, because hipsters don't digest DNA.
3) The GMO DNA makes it way up into the brain.
4) the GMO DNA somehow gets into all or most of the cells in the brain.
5) The GMO DNA somehow manages to slice its way into our genome in the nucleus.
6) In a way so that the GMO DNA is actually expressed into protein.
7) This extra copy of GMO DNA has a dominant effect over the naturally occurring gene.
8) But all this only happens only to that new piece of GMO DNA that codes for the Parkinson defect. The brain doesn't otherwise turn into a plant.

I guess not, but I'm struggling to get my head around what you mean.

That said, I really do wish biomedical science was much more open. Few things get me as riled up as IP shenanigans blocking sciencific progress. :/

. Not identical, and I'm not sure exactly what you are after with your list of buzzwords, but seems pretty related, no?
lol, nope but the words would fit in a way.
i've been reading about some depressed dudes in here and found http://www.nature.com/news/sperm-rna-carries-marks-of-trauma-1.15049
Trauma’s impact comes partly from social factors, such as its influence on how parents interact with their children. But stress also leaves ‘epigenetic marks’ — chemical changes that affect how DNA is expressed without altering its sequence. A study published this week in Nature Neuroscience finds that stress in early life alters the production of small RNAs, called microRNAs, in the sperm of mice. The mice show depressive behaviours that persist in their progeny, which also show glitches in metabolism.
...
In the new study, Isabelle Mansuy, a neuroscientist at the University of Zurich, Switzerland, and her colleagues periodically separated mother mice from their young pups and exposed the mothers to stressful situations — either by placing them in cold water or physically restraining them. These separations occurred every day but at erratic times, so that the mothers could not comfort their pups (termed the F1 generation) with extra cuddling before separation.

When raised this way, male offspring showed depressive behaviours and tended to underestimate risk, the study found. Their sperm also showed abnormally high expression of five microRNAs. One of these, miR-375, has been linked to stress and regulation of metabolism.

The F1 males’ offspring, the F2 generation, showed similar depressive behaviours, as well as abnormal sugar metabolism. The F1 and F2 generations also had abnormal levels of the five microRNAs in their blood and in the hippocampus, a brain region involved in stress responses. Behavioural effects persisted in the F3 generation as well.
so if they can't/won't get cured, at least they should not breed.

or, i can even pin "a fetus is a human being" on this and be right; it understands/shares my pain!.

Edit: or refugees, war refugees. they would have depressed/stressed, fearless children prone to act up.

Probably just another nature paper that won't stand up to replication attempts. Dodgy stats without properly accounting for biological variance, p-hacking, publishing bias, impact bias, and all that. If you read on they talk about limitations and inconsistencies in their data.

I won't go into the ethics discussion you are trying to provoke.
but that's why this is fun, it's unknown territory. besides, the results can and are replicated in more/different experiments/studies + Show Spoiler +
Recent studies have suggested that physiological and behavioral traits may be transgenerationally inherited through the paternal lineage, possibly via non-genomic signals derived from the sperm. To investigate how paternal stress might influence offspring behavioral phenotypes, a model of hypothalamic–pituitary–adrenal (HPA) axis dysregulation was used. Male breeders were administered water supplemented with corticosterone (CORT) for 4 weeks before mating with untreated female mice. Female, but not male, F1 offspring of CORT-treated fathers displayed altered fear extinction at 2 weeks of age. Only male F1 offspring exhibited altered patterns of ultrasonic vocalization at postnatal day 3 and, as adults, showed decreased time in open on the elevated-plus maze and time in light on the light–dark apparatus, suggesting a hyperanxiety-like behavioral phenotype due to paternal CORT treatment. Interestingly, expression of the paternally imprinted gene Igf2 was increased in the hippocampus of F1 male offspring but downregulated in female offspring. Male and female F2 offspring displayed increased time spent in the open arm of the elevated-plus maze, suggesting lower levels of anxiety compared with control animals. Only male F2 offspring showed increased immobility time on the forced-swim test and increased latency to feed on the novelty-supressed feeding test, suggesting a depression-like phenotype in these animals. Collectively, these data provide evidence that paternal CORT treatment alters anxiety and depression-related behaviors across multiple generations. Analysis of the small RNA profile in sperm from CORT-treated males revealed marked effects on the expression of small noncoding RNAs. Sperm from CORT-treated males contained elevated levels of three microRNAs, miR-98, miR-144 and miR-190b, which are predicted to interact with multiple growth factors, including Igf2 and Bdnf. Sustained elevation of glucocorticoids is therefore involved in the transmission of paternal stress-induced traits across generations in a process involving small noncoding RNA signals transmitted by the male germline. +
or this, which summarizes the whole situation nicely:

Significance

Increasing evidence suggests that certain acquired traits can be transmitted to the next generation. However, controversy over the inheritance of acquired traits remains, as the exact molecular and mechanistic basis for these observations remains largely unclear. In this study, using a nongenetic prediabetes mouse model, we have shown that environmentally induced epigenetic alterations in sperm can be inherited to the next generation. Paternal prediabetic conditions affect epigenetic marks in offspring and can be inherited for several generations. This finding provides a molecular basis for the inheritance of acquired traits and may have implications in explaining the prevalence of obesity, type 2 diabetes, and other chronic metabolic diseases.
Abstract

The global prevalence of prediabetes and type 2 diabetes (T2D) is increasing, and it is contributing to the susceptibility to diabetes and its related epidemic in offspring. Although the impacts of paternal impaired fasting blood glucose and glucose intolerance on the metabolism of offspring have been well established, the exact molecular and mechanistic basis that mediates these impacts remains largely unclear. Here we show that paternal prediabetes increases the susceptibility to diabetes in offspring through gametic epigenetic alterations. In our findings, paternal prediabetes led to glucose intolerance and insulin resistance in offspring. Relative to controls, offspring of prediabetic fathers exhibited altered gene expression patterns in the pancreatic islets, with down-regulation of several genes involved in glucose metabolism and insulin signaling pathways. Epigenomic profiling of offspring pancreatic islets revealed numerous changes in cytosine methylation depending on paternal prediabetes, including reproducible changes in methylation over several insulin signaling genes. Paternal prediabetes altered overall methylome patterns in sperm, with a large portion of differentially methylated genes overlapping with that of pancreatic islets in offspring. Our study uniquely revealed that prediabetes can be inherited transgenerationally through the mammalian germ line by an epigenetic mechanism.
+
, it's the means of transmission that is not totally understood.
there a whole field of study https://en.wikipedia.org/wiki/Epigenetics#Mechanisms coming up with new findings yearly.

(and talking about Trump is booooooooorringgggggggggggg unless you're an american.)

Ah, yeah, paper is from 2014. I still am not convinced, but as I have no intention of going through a proper lit review on the subject, I retract the previous statement.

And how is sterilising people with (believed) flawed inheritable traits unknown territory? The discussion has been very relevant from thew start of genetics. Indeed, already the nazis suggested very similar things (it wasn't popular).

In genetics (as you may know?), standard procedure is to see a genetic counselor, that then judges case by case whether the individual should be informed about the genetic defects or not. In general, to do anything at all, they want very strong evidence that the genetic trait is actually causing, and they prefer it to be actionable, in the sense that maybe you can also test your partner, or do in vitro fertilization and select an egg that doesn't have the defect, or something like that. At that point they sometimes inform the individual, and it is then up to them to choose what they want to do.

Sterilizing certainly is never on the table. And I don't think there is any believed inheritable epigenetic (or this miRNA thing) trait, that has anywhere close to sufficient evidence of cause for a genetic counselor to consider mentioning it. If you go to a naturopath or whatever they are called, then it's a completely different story of course.
when i said they should not breed, i was thinking it would be a choice, their choice; as in, they grow a conscience and decide not to do it.
but since you went there, i wouldn't sterilize them but i'll make sure those involved know about it(the female, then later the offspring); i'd enforce a mandatory informing of parties.
there would still be some problematic issues in a case by case scenario like:
- if depression is passed on and it's a severe form, suicidal thoughts/actions and what not, it would probably require some actioning(infecting someone with HIV for ex., is a criminal offense on par with murder in some countries). but even then, managing the consequences might be preferred to a total removal from the gene pool(it stops spreading from the third generation so it would be a rational balancing act in some cases).

genetic counseling is a very new thing here(couple years at best) and there's only one city in the country that provides that service/guidance; you'd normally talk to your family doctor and he'll have some understanding/knowledge about those disorders. but, i think those are on a totally different level than the temporary(fixed number of generations depending on what's being passed on) inheritance passed on through epigenetics.

overall, you went pretty far from where i was coming from, with your reply.
i was mostly thinking of immediate steps one could take to avoid passing on mild inconveniences(pamper those males else your kids would be screwed kind of thing), i was seeing reasons for which females seek in their males fitness while males don't care about the fitness in a female(within reason; they don't pass things on to the next generation(so far at least, pending more research)), exercising choice and assuming the outcome on a personal and societal level.
And my fury stands ready. I bring all your plans to nought. My bleak heart beats steady. 'Tis you whom I have sought.
xM(Z
Profile Joined November 2006
Romania5299 Posts
February 10 2017 08:44 GMT
#11743
On February 10 2017 01:05 Buckyman wrote:
Re: Airplane on a conveyer belt
Can an airplane gain forward speed if it's on a conveyer belt moving the opposite direction? Yes, the wheels just end up spinning faster.
Can an airplane take off if it's somehow prevented from gaining forward speed? Not for most airplane designs.

----
Re: Water to the Moon
This question was just barely sane enough to be discussable. And the (partial) answer was interesting enough to be worth discussing.
you fit the conveyer with blades/vanes that would create vertical lift then the plane engine will create forward speed.
And my fury stands ready. I bring all your plans to nought. My bleak heart beats steady. 'Tis you whom I have sought.
AbouSV
Profile Joined October 2014
Germany1278 Posts
February 10 2017 14:35 GMT
#11744
I don't get the difference you see between having a plane going full thrust while keeping the breaks on (as they do at the start of a takeoff), and have no break, but being on a conveyor belt that has the same effect?
In both cases:
-The plane does not move
-There is wind behind
-But no lift is created (as the air flow is due the the reactor/propeller and does not interact with the wings)
Buckyman
Profile Joined May 2014
1364 Posts
February 10 2017 17:37 GMT
#11745
The breaks keep the middle of the wheel from moving relative to the bottom of the wheel.

The conveyer belt can move the bottom of the wheel, but that doesn't mean the middle of the wheel moves in the same direction.
Cascade
Profile Blog Joined March 2006
Australia5405 Posts
February 10 2017 23:29 GMT
#11746
On February 10 2017 17:24 xM(Z wrote:
Show nested quote +
On February 10 2017 09:22 Cascade wrote:
On February 09 2017 21:39 xM(Z wrote:
On February 09 2017 18:30 Cascade wrote:
On February 09 2017 17:33 xM(Z wrote:
On February 09 2017 17:09 Cascade wrote:
On February 09 2017 16:51 xM(Z wrote:
On February 09 2017 15:07 Cascade wrote:
On February 09 2017 03:38 xM(Z wrote:
epigenetics, depression, sperm, nature, microRNA, offsprings ... go!.

I'm pretty sure you tried that already, or something very similar. Or was that someone else? I think it was you...
wasn't me; what came out of it?.

I was thinking of your GMO antics + Show Spoiler +
On January 12 2017 15:23 Cascade wrote:
Show nested quote +
On January 12 2017 04:21 xM(Z wrote:
you mixed up my phrasing - protein signaling with protein digestion.
- protein signaling based on gene mutation(no one knows why it mutates but environmental as well as hereditary reasons are quoted) causes Parkinson;
- protein digestion - irritable bowel syndrome, autoimmune disorders and others

pepsin stops digesting nucleic acids(DNA) at ~8ph; with all them hipsters on pure alkaline diets, nothing is guaranteed.

I'm trying to understand here... Are you afraid that:

1) GMO plants will happen to have DNA that cause Parkinsons in humans, but the wild type plant doesn't.
2) We eat the GMOs, and the DNA somehow doesn't get digested, because hipsters don't digest DNA.
3) The GMO DNA makes it way up into the brain.
4) the GMO DNA somehow gets into all or most of the cells in the brain.
5) The GMO DNA somehow manages to slice its way into our genome in the nucleus.
6) In a way so that the GMO DNA is actually expressed into protein.
7) This extra copy of GMO DNA has a dominant effect over the naturally occurring gene.
8) But all this only happens only to that new piece of GMO DNA that codes for the Parkinson defect. The brain doesn't otherwise turn into a plant.

I guess not, but I'm struggling to get my head around what you mean.

That said, I really do wish biomedical science was much more open. Few things get me as riled up as IP shenanigans blocking sciencific progress. :/

. Not identical, and I'm not sure exactly what you are after with your list of buzzwords, but seems pretty related, no?
lol, nope but the words would fit in a way.
i've been reading about some depressed dudes in here and found http://www.nature.com/news/sperm-rna-carries-marks-of-trauma-1.15049
Trauma’s impact comes partly from social factors, such as its influence on how parents interact with their children. But stress also leaves ‘epigenetic marks’ — chemical changes that affect how DNA is expressed without altering its sequence. A study published this week in Nature Neuroscience finds that stress in early life alters the production of small RNAs, called microRNAs, in the sperm of mice. The mice show depressive behaviours that persist in their progeny, which also show glitches in metabolism.
...
In the new study, Isabelle Mansuy, a neuroscientist at the University of Zurich, Switzerland, and her colleagues periodically separated mother mice from their young pups and exposed the mothers to stressful situations — either by placing them in cold water or physically restraining them. These separations occurred every day but at erratic times, so that the mothers could not comfort their pups (termed the F1 generation) with extra cuddling before separation.

When raised this way, male offspring showed depressive behaviours and tended to underestimate risk, the study found. Their sperm also showed abnormally high expression of five microRNAs. One of these, miR-375, has been linked to stress and regulation of metabolism.

The F1 males’ offspring, the F2 generation, showed similar depressive behaviours, as well as abnormal sugar metabolism. The F1 and F2 generations also had abnormal levels of the five microRNAs in their blood and in the hippocampus, a brain region involved in stress responses. Behavioural effects persisted in the F3 generation as well.
so if they can't/won't get cured, at least they should not breed.

or, i can even pin "a fetus is a human being" on this and be right; it understands/shares my pain!.

Edit: or refugees, war refugees. they would have depressed/stressed, fearless children prone to act up.

Probably just another nature paper that won't stand up to replication attempts. Dodgy stats without properly accounting for biological variance, p-hacking, publishing bias, impact bias, and all that. If you read on they talk about limitations and inconsistencies in their data.

I won't go into the ethics discussion you are trying to provoke.
but that's why this is fun, it's unknown territory. besides, the results can and are replicated in more/different experiments/studies + Show Spoiler +
Recent studies have suggested that physiological and behavioral traits may be transgenerationally inherited through the paternal lineage, possibly via non-genomic signals derived from the sperm. To investigate how paternal stress might influence offspring behavioral phenotypes, a model of hypothalamic–pituitary–adrenal (HPA) axis dysregulation was used. Male breeders were administered water supplemented with corticosterone (CORT) for 4 weeks before mating with untreated female mice. Female, but not male, F1 offspring of CORT-treated fathers displayed altered fear extinction at 2 weeks of age. Only male F1 offspring exhibited altered patterns of ultrasonic vocalization at postnatal day 3 and, as adults, showed decreased time in open on the elevated-plus maze and time in light on the light–dark apparatus, suggesting a hyperanxiety-like behavioral phenotype due to paternal CORT treatment. Interestingly, expression of the paternally imprinted gene Igf2 was increased in the hippocampus of F1 male offspring but downregulated in female offspring. Male and female F2 offspring displayed increased time spent in the open arm of the elevated-plus maze, suggesting lower levels of anxiety compared with control animals. Only male F2 offspring showed increased immobility time on the forced-swim test and increased latency to feed on the novelty-supressed feeding test, suggesting a depression-like phenotype in these animals. Collectively, these data provide evidence that paternal CORT treatment alters anxiety and depression-related behaviors across multiple generations. Analysis of the small RNA profile in sperm from CORT-treated males revealed marked effects on the expression of small noncoding RNAs. Sperm from CORT-treated males contained elevated levels of three microRNAs, miR-98, miR-144 and miR-190b, which are predicted to interact with multiple growth factors, including Igf2 and Bdnf. Sustained elevation of glucocorticoids is therefore involved in the transmission of paternal stress-induced traits across generations in a process involving small noncoding RNA signals transmitted by the male germline. +
or this, which summarizes the whole situation nicely:

Significance

Increasing evidence suggests that certain acquired traits can be transmitted to the next generation. However, controversy over the inheritance of acquired traits remains, as the exact molecular and mechanistic basis for these observations remains largely unclear. In this study, using a nongenetic prediabetes mouse model, we have shown that environmentally induced epigenetic alterations in sperm can be inherited to the next generation. Paternal prediabetic conditions affect epigenetic marks in offspring and can be inherited for several generations. This finding provides a molecular basis for the inheritance of acquired traits and may have implications in explaining the prevalence of obesity, type 2 diabetes, and other chronic metabolic diseases.
Abstract

The global prevalence of prediabetes and type 2 diabetes (T2D) is increasing, and it is contributing to the susceptibility to diabetes and its related epidemic in offspring. Although the impacts of paternal impaired fasting blood glucose and glucose intolerance on the metabolism of offspring have been well established, the exact molecular and mechanistic basis that mediates these impacts remains largely unclear. Here we show that paternal prediabetes increases the susceptibility to diabetes in offspring through gametic epigenetic alterations. In our findings, paternal prediabetes led to glucose intolerance and insulin resistance in offspring. Relative to controls, offspring of prediabetic fathers exhibited altered gene expression patterns in the pancreatic islets, with down-regulation of several genes involved in glucose metabolism and insulin signaling pathways. Epigenomic profiling of offspring pancreatic islets revealed numerous changes in cytosine methylation depending on paternal prediabetes, including reproducible changes in methylation over several insulin signaling genes. Paternal prediabetes altered overall methylome patterns in sperm, with a large portion of differentially methylated genes overlapping with that of pancreatic islets in offspring. Our study uniquely revealed that prediabetes can be inherited transgenerationally through the mammalian germ line by an epigenetic mechanism.
+
, it's the means of transmission that is not totally understood.
there a whole field of study https://en.wikipedia.org/wiki/Epigenetics#Mechanisms coming up with new findings yearly.

(and talking about Trump is booooooooorringgggggggggggg unless you're an american.)

Ah, yeah, paper is from 2014. I still am not convinced, but as I have no intention of going through a proper lit review on the subject, I retract the previous statement.

And how is sterilising people with (believed) flawed inheritable traits unknown territory? The discussion has been very relevant from thew start of genetics. Indeed, already the nazis suggested very similar things (it wasn't popular).

In genetics (as you may know?), standard procedure is to see a genetic counselor, that then judges case by case whether the individual should be informed about the genetic defects or not. In general, to do anything at all, they want very strong evidence that the genetic trait is actually causing, and they prefer it to be actionable, in the sense that maybe you can also test your partner, or do in vitro fertilization and select an egg that doesn't have the defect, or something like that. At that point they sometimes inform the individual, and it is then up to them to choose what they want to do.

Sterilizing certainly is never on the table. And I don't think there is any believed inheritable epigenetic (or this miRNA thing) trait, that has anywhere close to sufficient evidence of cause for a genetic counselor to consider mentioning it. If you go to a naturopath or whatever they are called, then it's a completely different story of course.
when i said they should not breed, i was thinking it would be a choice, their choice; as in, they grow a conscience and decide not to do it.
but since you went there, i wouldn't sterilize them but i'll make sure those involved know about it(the female, then later the offspring); i'd enforce a mandatory informing of parties.
there would still be some problematic issues in a case by case scenario like:
- if depression is passed on and it's a severe form, suicidal thoughts/actions and what not, it would probably require some actioning(infecting someone with HIV for ex., is a criminal offense on par with murder in some countries). but even then, managing the consequences might be preferred to a total removal from the gene pool(it stops spreading from the third generation so it would be a rational balancing act in some cases).

genetic counseling is a very new thing here(couple years at best) and there's only one city in the country that provides that service/guidance; you'd normally talk to your family doctor and he'll have some understanding/knowledge about those disorders. but, i think those are on a totally different level than the temporary(fixed number of generations depending on what's being passed on) inheritance passed on through epigenetics.

overall, you went pretty far from where i was coming from, with your reply.
i was mostly thinking of immediate steps one could take to avoid passing on mild inconveniences(pamper those males else your kids would be screwed kind of thing), i was seeing reasons for which females seek in their males fitness while males don't care about the fitness in a female(within reason; they don't pass things on to the next generation(so far at least, pending more research)), exercising choice and assuming the outcome on a personal and societal level.

If the science isn't solid, do you inform though? I think you agree that you shouldn't. Telling someone that they have an inheritable defect is incredibly stressful an has a huge impact on their lives. You don't want false positives. And the paper you cite isn't anywhere close to enough to start informing people.
Blisse
Profile Blog Joined July 2010
Canada3710 Posts
February 14 2017 01:27 GMT
#11747
Been watching a lot of snooker videos, play billiards recreationally (poorly).

Why does it seem like snooker pros are so much better than billiards pros? Like I'll seem billiards pros miss their next position so much more often. Is it just personal bias? Or is there something I'm missing?
There is no one like you in the universe.
mustaju
Profile Blog Joined May 2010
Estonia4505 Posts
February 14 2017 06:19 GMT
#11748
After an Arterial Blood Gas test drew blood from my Ulnar artery, I experienced an uncomfortable numbness when I stretch the arm out. This has been ongoing for a week and I'd like to know how long I can expect this to continue.
WriterBrows somewhat high. https://www.youtube.com/watch?v=ndFysO2JunE
xM(Z
Profile Joined November 2006
Romania5299 Posts
Last Edited: 2017-02-14 07:11:37
February 14 2017 07:11 GMT
#11749
it's called acute compartment syndrome; if left by itself it can get better or it can get worse based on the source/cause of the blockage. if it gets worse you'll begin to have other symptoms: persistent numbing, swelling, discoloration of the arm in that region, some paralysis maybe.
(nsfw) https://en.wikipedia.org/wiki/Compartment_syndrome
And my fury stands ready. I bring all your plans to nought. My bleak heart beats steady. 'Tis you whom I have sought.
Cascade
Profile Blog Joined March 2006
Australia5405 Posts
February 14 2017 07:16 GMT
#11750
On February 14 2017 15:19 mustaju wrote:
After an Arterial Blood Gas test drew blood from my Ulnar artery, I experienced an uncomfortable numbness when I stretch the arm out. This has been ongoing for a week and I'd like to know how long I can expect this to continue.

Of all of internet, you have definitely come to the right place for medical advice! Congratulations!

Based on absolutely nothing, you can expect this to peter off in the coming 1-2 weeks or so. Further making up numbers and facts from thin air, I recommend you to return for further tests (such as knee reflex tests and throat swab) if it still persists in two weeks. Providing more lies for good measure, if you wait much longer you risk it deteriorating into bubonic plague, and your arm (and probably legs) will have to be amputated.

+ Show Spoiler +
Anything the doctors say is FAKE. Sad.
mustaju
Profile Blog Joined May 2010
Estonia4505 Posts
February 14 2017 07:46 GMT
#11751
On February 14 2017 16:16 Cascade wrote:
Show nested quote +
On February 14 2017 15:19 mustaju wrote:
After an Arterial Blood Gas test drew blood from my Ulnar artery, I experienced an uncomfortable numbness when I stretch the arm out. This has been ongoing for a week and I'd like to know how long I can expect this to continue.

Of all of internet, you have definitely come to the right place for medical advice! Congratulations!

Based on absolutely nothing, you can expect this to peter off in the coming 1-2 weeks or so. Further making up numbers and facts from thin air, I recommend you to return for further tests (such as knee reflex tests and throat swab) if it still persists in two weeks. Providing more lies for good measure, if you wait much longer you risk it deteriorating into bubonic plague, and your arm (and probably legs) will have to be amputated.

+ Show Spoiler +
Anything the doctors say is FAKE. Sad.

It's the dumb questions thread. I did not want to pester my doctor over something that seems very likely to go away on it's own. Thanks for the replies! ^^
WriterBrows somewhat high. https://www.youtube.com/watch?v=ndFysO2JunE
farvacola
Profile Blog Joined January 2011
United States18857 Posts
Last Edited: 2017-02-14 12:18:29
February 14 2017 12:17 GMT
#11752
The numbness likely relates to inflammation at the point of withdrawal pushing up against the ulnar nerve. It'll almost certainly return to normal, but should the numbness continue for a couple weeks, I'd seek out a doctor.

Disclaimer: I'm not a doctor
"when the Dead Kennedys found out they had skinhead fans, they literally wrote a song titled 'Nazi Punks Fuck Off'"
Cascade
Profile Blog Joined March 2006
Australia5405 Posts
February 14 2017 13:18 GMT
#11753
On February 14 2017 16:46 mustaju wrote:
Show nested quote +
On February 14 2017 16:16 Cascade wrote:
On February 14 2017 15:19 mustaju wrote:
After an Arterial Blood Gas test drew blood from my Ulnar artery, I experienced an uncomfortable numbness when I stretch the arm out. This has been ongoing for a week and I'd like to know how long I can expect this to continue.

Of all of internet, you have definitely come to the right place for medical advice! Congratulations!

Based on absolutely nothing, you can expect this to peter off in the coming 1-2 weeks or so. Further making up numbers and facts from thin air, I recommend you to return for further tests (such as knee reflex tests and throat swab) if it still persists in two weeks. Providing more lies for good measure, if you wait much longer you risk it deteriorating into bubonic plague, and your arm (and probably legs) will have to be amputated.

+ Show Spoiler +
Anything the doctors say is FAKE. Sad.

It's the dumb questions thread. I did not want to pester my doctor over something that seems very likely to go away on it's own. Thanks for the replies! ^^

Oh I'm not saying your shouldn't post here as in you'll be banned. I'm saying you shouldn't trust the answers.

A 5-10 min internet search will give you more reliable information I think.
Zambrah
Profile Blog Joined June 2011
United States7393 Posts
February 14 2017 13:29 GMT
#11754
On February 14 2017 22:18 Cascade wrote:
Show nested quote +
On February 14 2017 16:46 mustaju wrote:
On February 14 2017 16:16 Cascade wrote:
On February 14 2017 15:19 mustaju wrote:
After an Arterial Blood Gas test drew blood from my Ulnar artery, I experienced an uncomfortable numbness when I stretch the arm out. This has been ongoing for a week and I'd like to know how long I can expect this to continue.

Of all of internet, you have definitely come to the right place for medical advice! Congratulations!

Based on absolutely nothing, you can expect this to peter off in the coming 1-2 weeks or so. Further making up numbers and facts from thin air, I recommend you to return for further tests (such as knee reflex tests and throat swab) if it still persists in two weeks. Providing more lies for good measure, if you wait much longer you risk it deteriorating into bubonic plague, and your arm (and probably legs) will have to be amputated.

+ Show Spoiler +
Anything the doctors say is FAKE. Sad.

It's the dumb questions thread. I did not want to pester my doctor over something that seems very likely to go away on it's own. Thanks for the replies! ^^

Oh I'm not saying your shouldn't post here as in you'll be banned. I'm saying you shouldn't trust the answers.

A 5-10 min internet search will give you more reliable information I think.


But we can google for him and then we get to repeat the information and feel like medical professionals!

Also, it almost certainly needs to be amputated.
Incremental change is the Democrat version of Trickle Down economics.
Acrofales
Profile Joined August 2010
Spain18292 Posts
February 14 2017 13:36 GMT
#11755
On February 14 2017 15:19 mustaju wrote:
After an Arterial Blood Gas test drew blood from my Ulnar artery, I experienced an uncomfortable numbness when I stretch the arm out. This has been ongoing for a week and I'd like to know how long I can expect this to continue.

That's what they said they were doing. But given your symptoms, the only thing that makes sense was that they were actually injecting nanobots so that the reptilians can monitor you. The only fix is to expose yourself to an EMP blast, which will depower the nanobots and allow your body to flush them out.
Dark_Chill
Profile Joined May 2011
Canada3353 Posts
February 14 2017 14:05 GMT
#11756
I feel like TL tends to have more google-literate people than average. So, it seems reasonable to assume that asking people here to help you search would lead to decent results, maybe better than you yourself could get (following weird links, not checking multiple searches, etc).
CUTE MAKES RIGHT
JimmiC
Profile Blog Joined May 2011
Canada22817 Posts
February 14 2017 14:16 GMT
#11757
--- Nuked ---
mustaju
Profile Blog Joined May 2010
Estonia4505 Posts
February 14 2017 14:23 GMT
#11758
On February 14 2017 23:16 JimmiC wrote:
Yeah but how you could you possibly tell the real.searchers from the guys making it up? Does he emo blast him self? Or amputate? It Or just leave it? Tough call.

I presume this to be an extremely standard procedure. Hence, likely to get a good reply. I am totes going for the amputation btw.

P.S. It was massively helpful in that i learned terminology! Superhappy camper here.
WriterBrows somewhat high. https://www.youtube.com/watch?v=ndFysO2JunE
JimmiC
Profile Blog Joined May 2011
Canada22817 Posts
February 14 2017 14:34 GMT
#11759
--- Nuked ---
farvacola
Profile Blog Joined January 2011
United States18857 Posts
February 14 2017 14:36 GMT
#11760
Are you really from Canada? I have a good friend who's parents emigrated from there. If you are can you tell me a popular dish or something interesting about it I can't find on a quick google search?
"when the Dead Kennedys found out they had skinhead fans, they literally wrote a song titled 'Nazi Punks Fuck Off'"
Prev 1 586 587 588 589 590 783 Next
Please log in or register to reply.
Live Events Refresh
Next event in 49m
[ Submit Event ]
Live Streams
Refresh
StarCraft 2
TKL 1378
mouzHeroMarine 66
StarCraft: Brood War
Sea 10418
Bisu 3288
Britney 1315
Jaedong 1239
EffOrt 912
Soulkey 603
BeSt 523
Mini 450
Light 345
firebathero 271
[ Show more ]
Hyuk 225
Rush 174
Pusan 110
Hyun 87
hero 84
scan(afreeca) 55
Sharp 51
Sea.KH 50
Backho 44
Aegong 43
ToSsGirL 39
sorry 39
soO 28
910 25
Sexy 21
Barracks 20
Movie 17
Terrorterran 15
Rock 12
zelot 12
GoRush 11
Noble 11
Dota 2
syndereN563
Counter-Strike
zeus856
byalli472
edward89
Other Games
singsing2794
B2W.Neo1381
hiko865
Liquid`RaSZi540
Lowko399
Hui .312
crisheroes293
monkeys_forever127
ArmadaUGS79
Trikslyr26
Organizations
Counter-Strike
PGL1558
Other Games
WardiTV545
StarCraft: Brood War
lovetv 9
StarCraft 2
Blizzard YouTube
StarCraft: Brood War
BSLTrovo
[ Show 16 non-featured ]
StarCraft 2
• StrangeGG 76
• AfreecaTV YouTube
• intothetv
• Kozan
• IndyKCrew
• LaughNgamezSOOP
• Migwel
• sooper7s
StarCraft: Brood War
• HerbMon 48
• Michael_bg 4
• BSLYoutube
• STPLYoutube
• ZZZeroYoutube
League of Legends
• Nemesis6233
Other Games
• WagamamaTV467
• Shiphtur189
Upcoming Events
Monday Night Weeklies
49m
Replay Cast
8h 49m
The PondCast
18h 49m
Kung Fu Cup
19h 49m
GSL
1d 18h
Cure vs sOs
SHIN vs ByuN
Replay Cast
2 days
GSL
2 days
Classic vs Solar
GuMiho vs Zoun
WardiTV Spring Champion…
2 days
Replay Cast
3 days
Sparkling Tuna Cup
3 days
[ Show More ]
WardiTV Spring Champion…
3 days
Replay Cast
4 days
RSL Revival
4 days
Classic vs SHIN
Rogue vs Bunny
BSL
5 days
Replay Cast
5 days
Afreeca Starleague
5 days
Flash vs Soma
RSL Revival
5 days
BSL
6 days
Patches Events
6 days
Universe Titan Cup
6 days
Rogue vs Percival
Wardi Open
6 days
Liquipedia Results

Completed

Escore Tournament S2: W7
2026 GSL S1
Nations Cup 2026

Ongoing

BSL Season 22
ASL Season 21
IPSL Spring 2026
KCM Race Survival 2026 Season 2
Acropolis #4
KK 2v2 League Season 1
BSL 22 Non-Korean Championship
YSL S3
SCTL 2026 Spring
RSL Revival: Season 5
Heroes Pulsing #1
Asian Champions League 2026
IEM Atlanta 2026
PGL Astana 2026
BLAST Rivals Spring 2026
IEM Rio 2026
PGL Bucharest 2026
Stake Ranked Episode 1
BLAST Open Spring 2026
ESL Pro League S23 Finals
ESL Pro League S23 Stage 1&2

Upcoming

Escore Tournament S2: W8
CSLAN 4
Kung Fu Cup 2026 Grand Finals
HSC XXIX
uThermal 2v2 2026 Main Event
Maestros of the Game 2
WardiTV Spring 2026
2026 GSL S2
Bounty Cup 2026
BLAST Bounty Summer 2026
BLAST Bounty Summer Qual
Stake Ranked Episode 3
XSE Pro League 2026
IEM Cologne Major 2026
Stake Ranked Episode 2
CS Asia Championships 2026
TLPD

1. ByuN
2. TY
3. Dark
4. Solar
5. Stats
6. Nerchio
7. sOs
8. soO
9. INnoVation
10. Elazer
1. Rain
2. Flash
3. EffOrt
4. Last
5. Bisu
6. Soulkey
7. Mini
8. Sharp
Sidebar Settings...

Advertising | Privacy Policy | Terms Of Use | Contact Us

Original banner artwork: Jim Warren
The contents of this webpage are copyright © 2026 TLnet. All Rights Reserved.