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Added a disclaimer on page 662. Many need to post better. |
I noted that there were only 94 total symptomatic cases in the 44.000 test group, so the 90% is not exactly s rock solid number, but I am very happy it seems to work!
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Usually the best source for commentary on vaccine and drug trial data is Derek Lowe from Science mag, he has some interesting points regarding the Pfizer data:
- since all the vaccine candidates in advanced trials target the spike protein, and all have shown to generate antibody responses, and this one worked, it's highly likely that all of them are going to work;
- The Pfizer vaccine (as well as the Moderna one iirc) requires -80ºc storage, so distribution will be a pain in the butt. It also requires two shots, 28 days apart.
https://blogs.sciencemag.org/pipeline/archives/2020/11/09/vaccine-efficacy-data
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I hope the vaccines are safe and effective and I hope they come as quickly as possible. Anti-vaxxers got a good demo of what it looks like when you don't vaccinate against a deadly disease.
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On November 10 2020 01:16 warding wrote:Usually the best source for commentary on vaccine and drug trial data is Derek Lowe from Science mag, he has some interesting points regarding the Pfizer data: - since all the vaccine candidates in advanced trials target the spike protein, and all have shown to generate antibody responses, and this one worked, it's highly likely that all of them are going to work; - The Pfizer vaccine (as well as the Moderna one iirc) requires -80ºc storage, so distribution will be a pain in the butt. It also requires two shots, 28 days apart. https://blogs.sciencemag.org/pipeline/archives/2020/11/09/vaccine-efficacy-data
Do you know what the division of labor (and IP) is between Pfizer and BionTech on their candidate?
American news seem to pretty universally describe it as the "Pfizer" vaccine, but the FT says "Pfizer and Biontech".
The case of the Oxford/AstraZena candidate makes more sense to me since one party in the collaboration is academic and not for profit, and the other is, well, not that. But both Pfizer and BionTech are publicly traded for profit companies no?
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They've probably got a profit sharing agreement of some sort already in place. Pfizer provides worldwide distribution and manufacturing facilities, and BionTech does the vaccine part IIRC.
I'm last in line to get it even if I could get it. Healthcare elderly, and anyone who works with elderly is well in front of me.
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Naturally US media would describe it as the Pfizer Vaccine, as it is a name they recognize. But yea, it is actually Biontech's vaccine (meaning they developed it), Pfizer helps with manufacturing, distributing etc.
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Bisutopia19352 Posts
Anyone get sick to their stomach watching all those students storm the Notre Dame field? I'm getting tired of the stupidity during this pandemic.
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On November 10 2020 05:34 BisuDagger wrote:
Anyone get sick to their stomach watching all those students storm the Notre Dame field? I'm getting tired of the stupidity during this pandemic.
Yeah it's disappointing to say the least. Rough stats I could find estimate that ~10% of the US had been infected with Covid as of October.
Watching worldometer trends is terrifying as an observer for the US as well(not that we're doing particularly hot where I am either, went from ~100 to 600 in the span of a couple months).
Week over week, there's been a ~40% increase in cases. The people infected then probably got it over Halloween, and there's still Thanksgiving and Christmas to come as major group holidays.
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Personal note, living in Spain. We just entered soft a soft lockdown, and I really hope it stops there. Crossing city borders can only be done with a valid reason, groups up to 6 people are not allowed and bars and restaurants are closed for a month. Schools work places and stores are not closed, and we can still go outside.
I actually don't mind this too much, as they are at least trying to target areas where the virus has spread the most. Some areas have experienced hospital overload already. Madrid has stabilized and is slowly declining using similar measures.
Both economically and socially, this is tough times for many, but it should be much easier than last time.
A blanket face mask obligation outside, on the other hand, is still utterly pointless, and was introduced long before the 2nd wave took off for all the wrong reasons. Long after it was obvious that the masks did not save Spain from a 2nd wave, people still kling to them as a cornerstone measure to stop the spread, which baffles me.
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What's scary is this page:
https://www.worldometers.info/coronavirus/country/us/
Sort it by Total cases/1m pop
N/S Dakota and Iowa are probably going to hit the 10% population officially infected mark pretty soon. The actual number is probably somewhere 1/3 to 2x that. Good luck to the states that didn't give a shit about the virus.
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Looks like the first batch of vaccines will be 50 mil enough for 25 million people (2 shots each). How many countries will those vaccines be split between and when is it most likely to hit the public? Late december?
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On November 10 2020 10:04 kidcrash wrote:
Looks like the first batch of vaccines will be 50 mil enough for 25 million people (2 shots each). How many countries will those vaccines be split between and when is it most likely to hit the public? Late december?
It's not really enough production to meaningfully vaccinate too many people. The wealthy and important (political leaders) will get the first doses, then some of the most vulnerable. Over the course of a year or two it'll have enough reach to finally blunt the momentum of the overall pandemic.
Mind you, this is already all based on rosy projections of production. No real chance of the vaccine ending a bloody winter.
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Everything sucked during this pandemic because of the mutual collaboration. Stated that all activities regarding to any field should be cancelled for your living existence in quarantine.
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On November 10 2020 13:14 LegalLord wrote:Show nested quote +On November 10 2020 10:04 kidcrash wrote:
Looks like the first batch of vaccines will be 50 mil enough for 25 million people (2 shots each). How many countries will those vaccines be split between and when is it most likely to hit the public? Late december? It's not really enough production to meaningfully vaccinate too many people. The wealthy and important (political leaders) will get the first doses, then some of the most vulnerable. Over the course of a year or two it'll have enough reach to finally blunt the momentum of the overall pandemic. Mind you, this is already all based on rosy projections of production. No real chance of the vaccine ending a bloody winter.
If distribution is a problem, I could just drive by their labs 
On a more serious note, apparently the German/EU government has not made binding contracts yet with Biontech/Pfizer.
Dafuq
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On November 10 2020 15:46 Harris1st wrote:Show nested quote +On November 10 2020 13:14 LegalLord wrote:On November 10 2020 10:04 kidcrash wrote:
Looks like the first batch of vaccines will be 50 mil enough for 25 million people (2 shots each). How many countries will those vaccines be split between and when is it most likely to hit the public? Late december? It's not really enough production to meaningfully vaccinate too many people. The wealthy and important (political leaders) will get the first doses, then some of the most vulnerable. Over the course of a year or two it'll have enough reach to finally blunt the momentum of the overall pandemic. Mind you, this is already all based on rosy projections of production. No real chance of the vaccine ending a bloody winter. If distribution is a problem, I could just drive by their labs On a more serious note, apparently the German/EU government has not made binding contracts yet with Biontech/Pfizer. Dafuq
I believe they were hesitant due to the relatively high price of their vaccine (around 20 Dollars per shot) compared to others which are about half of that. They (the EU) did draft a contract for 200 million doses back in September however. I'm 100% certain the german government is going to come out with news about a contract with Biontech within the next week.
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Ars did a breakdown of what the news means for the layman:
https://arstechnica.com/science/2020/11/heres-everything-to-know-about-pfizers-positive-vaccine-news/
It seems like the success of Pfizer also somewhat confirms that the other approaches will likely also produce a successful vaccine. If we could get 500m to vulnerable populations by March next year, and 1b+ by June, summer next year could be saved.
Still, the apparent early success of BNT162b2 bodes well for similar vaccines in development. The Coalition for Epidemic Preparedness Innovations (CEPI) celebrated the news, saying in a press statement:
“These are hugely positive and encouraging interim results and are testament to the ingenuity and skill of the scientific community in advancing vaccine candidates against COVID-19… We believe these interim results also increase the probability of success of other COVID-19 candidate vaccines which use a similar approach [pre-fusion spike as their immunogen], including all of the vaccines in the CEPI portfolio.”
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On November 10 2020 00:56 TT1 wrote:
cya covid
We still have months to go, sadly, and that's under the assumption that coronavirus is something that can actually be fully eradicated, rather than something that will continue to mutate and seasonally exist in our society (like an extremely bad, dangerous flu).
My school has had 7 coronavirus cases over the past 3 weeks, including 4 in the past 5 days. And this is *before* students come back to school - we currently just have teachers alone in their classrooms, acting as guinea pigs to see how badly coronavirus will be spread without hundreds of students walking through the hallways and moving from classroom to classroom.
The students come back to school on Monday, and the teachers are freaking out... And rightfully so. Apparently, the administration hasn't been telling the parents what's been happening in terms of coronavirus cases.
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On November 10 2020 07:06 Lmui wrote:What's scary is this page: https://www.worldometers.info/coronavirus/country/us/Sort it by Total cases/1m pop N/S Dakota and Iowa are probably going to hit the 10% population officially infected mark pretty soon. The actual number is probably somewhere 1/3 to 2x that. Good luck to the states that didn't give a shit about the virus.
Seing the rise in the US scares me about what's coming up for Brazil. Here cases have been going down for a few months, but both public policy and social adherence to distancing norms are turning very lax. At least we have the advantage that summer is starting.
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EPT
