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Smart Drugs / Brain Hacks - Page 5

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Deleted User 183001
Profile Joined May 2011
2939 Posts
March 19 2013 00:31 GMT
#81
On March 11 2013 15:49 Wrath 2.1 wrote:
deus ex inc :D

Oh dear no. :O

But everytime I put in my contact lenses, I think, "My vision is augmented." XD
ShcShc
Profile Joined October 2006
Canada912 Posts
Last Edited: 2013-03-19 00:40:38
March 19 2013 00:39 GMT
#82
On March 10 2013 14:04 wongfeihung wrote:
Show nested quote +
On March 10 2013 12:30 Epocalypse wrote:
Here's another video of the same guy in the OP video... He seems dopey to me, and I wouldn't take him as the best spokesman.


But he's a big wig in Silicon Valley
http://about.me/asprey

That dude talks like a computer. And it looks like he's staring into space the whole time. Also, why'd he shave half his eyebrows? That shit don't look good at all.


I actually ordered from his store.
His stuff is great. Bulletproof Coffee is actually pretty good.
I love EM Wave too (but then again, it complements my yoga).

MCT Oil, I'm not 100% sure on that yet (if you were never in a diet based on fat, its really hard on your stomach at the beginning).


About Onnit:
Alpha GPC is OK. I'm definitely unsure of the price you pay. If it does something, its definitely subtle.
New Mood: Haven't seen much difference.
God DAJNFBGHSfIDSHUKLFHSGUIO! -Jinro
ShcShc
Profile Joined October 2006
Canada912 Posts
March 19 2013 00:43 GMT
#83
On March 12 2013 07:50 JackDT wrote:
Oh boy Dave Asprey. He sells a ton of products and his methods for evaulating scientific evidence are atrocious. I cringe every time he brags on his blog about how many studies on subject X he read. Some examples of things he's selling:

Special coffee that isn't contaminated with toxins like all the other coffee you might drink.

Vibration plates to 'detox your immune system' http://www.bulletproofexec.com/bulletproof-vibe-whole-body-vibration-plate/

An "Earthing" Mat which grounds the body and he insists cures jet lag. http://www.upgradedself.com/tech/earthing-mat.html



No idea about the vibration or earthing. Sounds/looks gimmicky crap.
But his coffee is, honestly, the best.


God DAJNFBGHSfIDSHUKLFHSGUIO! -Jinro
Cel.erity
Profile Blog Joined September 2010
United States4890 Posts
March 19 2013 00:59 GMT
#84
On March 11 2013 07:12 Elegance wrote:
Show nested quote +
On March 10 2013 13:57 Ramiel wrote:
Vasopressin? Interesting. I am an ICU RN, we use this drug for ACLS protocols during cardiac arrest (usually during asystole along with another drug called atropine). I would assume that you would not be taking the vaso in high doses. Because Vaso is a 'pressor' or a medication that at a certain dose range clamps down on the vasculature to increase blood pressure. Most pressors (levophed, norepi, ext ext) are some nasty drugs. Normally they cannot be given peripherally, and in doing so you are damaging many organ systems, and peripheral extremities of the body when used for long periods (which can be a short as a number of days.)

So low dose vasopressin? I have heard of it used at some point for septic shock, but have no practice with it. So tacking vaso.... gives you an increased blood pressure. At lose dose I suppose that it could cause increased urine production. But normally vasopressin given at the clinical level clamps the renal artery down so hard, that you can throw a patient into kidney failure, from lack of blood passing through the kidney. (Imagine twisting a garden hose too tight... no water, or in this case blood goes through to the kidney.)

As for the rest of the drugs, they are usually used in urinary retention, and some for the treatment of narcolepsy... but other than vaso, i have very little clinical practice with any of them. If your looking to 'enhance' your brain function and activity- i would think a much safer, healther and cheaper way would be the following:

8 hours of sleep, 8 glasses of h2o a day, exercise.

But for the lasy people- you can always go and get some pseudoephedrine- this is the over the counter stimulant.

Found in:

Dayquil, pseudophed. That will give you a kick.

Edit:

Also holy shit, i was just looking through the ops list again, and i saw this-

Selegiline

That is an MAOI inhibitor. Normally last line in the use for anti-depressive medications. After SSRI, and tricyclics i think. (Not 100% sure on this, as i don't work psych) From what i remember from nursing school, MAOI's have some serious side effects, as well as dietary effects (ie eating certain foods, like cheese) can cause some wild idiosyncratic effects.

The fact that normal people would advocate the use of these drugs.... is pretty weird. Clinically, we use stimulants to increase function. Not any of the above.

Yeah MAOI's are pretty bad. Lots of things that you can't do while taking MAOI (including eating chocolate). Could fuck up your blood pressure or give you serotonin syndrome. Anyhow good to see a fellow nurse


This isn't entirely correct, as selegiline is a MAO-B inhibitor and will not inhibit MAO-A at low doses, so no dietary restrictions, though I don't know what dosage they're recommending for nootropic effects. Serotonin syndrome is also almost nonexistent in MAOI's; one of their few advantages over the more commonly prescribed SSRI's is their relative lack of side effects.
We found Dove in a soapless place.
Spiffeh
Profile Joined May 2010
United States830 Posts
March 19 2013 01:04 GMT
#85
Whatever "goal" you're striving for by taking nootropics, you can get 90% there by eating a clean diet and taking basic supplements. The next 10%, imo, is wayy too risky for the reward you're going to get.

If you're doing this as a means unto itself, then this doesn't apply to you, but if you're doing this as a means to an end, in order to perform better in your daily life, you're better off staying away until substantial studies come out that give the okay, or at the very least until these substances are tested by more people.
calgar
Profile Blog Joined November 2007
United States1277 Posts
March 19 2013 01:39 GMT
#86
On March 19 2013 09:43 ShcShc wrote:
Show nested quote +
On March 12 2013 07:50 JackDT wrote:
Oh boy Dave Asprey. He sells a ton of products and his methods for evaulating scientific evidence are atrocious. I cringe every time he brags on his blog about how many studies on subject X he read. Some examples of things he's selling:

Special coffee that isn't contaminated with toxins like all the other coffee you might drink.

Vibration plates to 'detox your immune system' http://www.bulletproofexec.com/bulletproof-vibe-whole-body-vibration-plate/

An "Earthing" Mat which grounds the body and he insists cures jet lag. http://www.upgradedself.com/tech/earthing-mat.html



No idea about the vibration or earthing. Sounds/looks gimmicky crap.
But his coffee is, honestly, the best.


What 'toxins' are absent that make it more expensive than Starbucks brand (or any other reputable brand)? Do you know that it's not just repackaged folgers? Everything else on the site screams scam so I'm going to guess the coffee is extremely plain and just overpriced. A fool and his money are soon parted, as the saying goes.
Cel.erity
Profile Blog Joined September 2010
United States4890 Posts
March 19 2013 02:03 GMT
#87
On March 19 2013 10:39 calgar wrote:
Show nested quote +
On March 19 2013 09:43 ShcShc wrote:
On March 12 2013 07:50 JackDT wrote:
Oh boy Dave Asprey. He sells a ton of products and his methods for evaulating scientific evidence are atrocious. I cringe every time he brags on his blog about how many studies on subject X he read. Some examples of things he's selling:

Special coffee that isn't contaminated with toxins like all the other coffee you might drink.

Vibration plates to 'detox your immune system' http://www.bulletproofexec.com/bulletproof-vibe-whole-body-vibration-plate/

An "Earthing" Mat which grounds the body and he insists cures jet lag. http://www.upgradedself.com/tech/earthing-mat.html



No idea about the vibration or earthing. Sounds/looks gimmicky crap.
But his coffee is, honestly, the best.


What 'toxins' are absent that make it more expensive than Starbucks brand (or any other reputable brand)? Do you know that it's not just repackaged folgers? Everything else on the site screams scam so I'm going to guess the coffee is extremely plain and just overpriced. A fool and his money are soon parted, as the saying goes.


It's a common psychological trick. Reminds me of this Bullshit episode about bottled water:

We found Dove in a soapless place.
ShcShc
Profile Joined October 2006
Canada912 Posts
Last Edited: 2013-03-19 03:10:21
March 19 2013 03:05 GMT
#88
On March 19 2013 10:39 calgar wrote:
Show nested quote +
On March 19 2013 09:43 ShcShc wrote:
On March 12 2013 07:50 JackDT wrote:
Oh boy Dave Asprey. He sells a ton of products and his methods for evaulating scientific evidence are atrocious. I cringe every time he brags on his blog about how many studies on subject X he read. Some examples of things he's selling:

Special coffee that isn't contaminated with toxins like all the other coffee you might drink.

Vibration plates to 'detox your immune system' http://www.bulletproofexec.com/bulletproof-vibe-whole-body-vibration-plate/

An "Earthing" Mat which grounds the body and he insists cures jet lag. http://www.upgradedself.com/tech/earthing-mat.html



No idea about the vibration or earthing. Sounds/looks gimmicky crap.
But his coffee is, honestly, the best.


What 'toxins' are absent that make it more expensive than Starbucks brand (or any other reputable brand)? Do you know that it's not just repackaged folgers? Everything else on the site screams scam so I'm going to guess the coffee is extremely plain and just overpriced. A fool and his money are soon parted, as the saying goes.



Its OK if you are skeptical. I was too.
Worst-case scenario is I would lose out on 20 bucks (or between 5-10$ opportunity costs) and on the up-side, I would find a great new product (which imo, it is a great product). Not much to lose honestly. And I did use products (e.g: Alpha GPC, Piracetam) which I didn't find that great, but that's OK too.

Its better to know than to be in the dark.
A lot of the great things in life came from not being afraid of trying something new or being proven wrong over something I was highly skeptical of.


I've worked at a Starbucks for a few years when I was much younger and I genuinely like Bulletproof Coffee a lot more.
I never completely tolerated other coffee since I was in HS almost a decade ago (random bouts of odd depression/), but with BP, it definitely feels different.

So this isin't about: "here are documents X and Y proving that toxins don't exist in this coffee and I went to the laboratories to double-check his claims". Its just: "try it and maybe, just maybe you'l love it too "

I'm sure you've heard of: "never be afraid of making a mistake".
This applies to the big things in life and to the small things too (such as the case here).


Cheers!
Shc



God DAJNFBGHSfIDSHUKLFHSGUIO! -Jinro
FoxShine
Profile Joined January 2012
United States156 Posts
Last Edited: 2013-03-19 04:34:50
March 19 2013 04:33 GMT
#89
I have tried piracetam, aniracetam, and oxiracetan. I wanted to get pramiracetam as it is much more potent, iv been unable to find a source for bulk powder. I paired them all with a Choline supplement... One thing i definitely noticed is my short term memory was much better.. I also found it a bit easier to think about things as if my thoughts were clearer. I'm guessing this is the "brain-fog" its supposed to help with. Aniracetam seemed to give me more typos.. don't know what that's about. I know that Pramiracetam and phenyl-piracetam are the most potent of the racetams.. and β-Phenyl-γ-aminobutyric acid (phenibut) is pretty powerful.. For anyone looking to try them i reccomend a choline supplement because it seems to be more effective or atleast synergistic with the lesser racetams. -researched a few years ago information could be slightly inaccurate.
We do what we must, because we can
xContagion
Profile Joined July 2012
United States40 Posts
Last Edited: 2013-03-19 05:19:44
March 19 2013 05:17 GMT
#90
What happens when people become dependent on these drugs within the next 3 years? This is just the elite, doing what they do indoctrinating society on their new agenda of genetic mutation and transhumanism. Sounds nuts? So did Elivs being allowed to shake his hops wildly on T.V. literally ONLY 50yrs. ago. Slowly but surely. First it's this to "better your brain" then it's "I need this to better my whatever" then before you know you're just desensitized to it and you need everything that's on the market for you to "better yourself". Just be cautious, God has given you what you need. There;s always side effects, when you think about it nothing like this "just works" for free.
ZERG_RUSSIAN
Profile Blog Joined November 2008
10417 Posts
Last Edited: 2013-03-19 06:39:21
March 19 2013 06:30 GMT
#91
On March 19 2013 14:17 xContagion wrote:
What happens when people become dependent on these drugs within the next 3 years? This is just the elite, doing what they do indoctrinating society on their new agenda of genetic mutation and transhumanism. Sounds nuts? So did Elivs being allowed to shake his hops wildly on T.V. literally ONLY 50yrs. ago. Slowly but surely. First it's this to "better your brain" then it's "I need this to better my whatever" then before you know you're just desensitized to it and you need everything that's on the market for you to "better yourself". Just be cautious, God has given you what you need. There;s always side effects, when you think about it nothing like this "just works" for free.

You're retarded, did you even look to see if there was an addiction potential?

There's none btw

[edit] Just so I don't sound like so much of a dick:

http://en.wikipedia.org/wiki/Nootropic#Nootropics_vs._cognitive_enhancers

Cognitive enhancers are drugs, supplements, nutraceuticals, and functional foods that enhance attentional control and memory.[5][6] Nootropics are cognitive enhancers that are neuroprotective or extremely nontoxic. Nootropics are by definition cognitive enhancers, but a cognitive enhancer is not necessarily a nootropic.
Giurgea's Nootropic Criteria:
Enhances learning and memory.
Enhance learned behaviors under conditions which are known to disrupt them. Example: hypoxia (oxygen deficiency).
Protect the brain from physical or chemical injury.
Enhance the tonic cortical/subcortical control mechanisms
Exhibit few side effects and extremely low toxicity, while lacking the pharmacology of typical psychotropic drugs (motor stimulation, sedation etc.).
Since Giurgea's original criteria were first published, there has been little agreement as to what truly constitutes a nootropic compound. The most well defined criteria to date was established by Skondia in 1979. Skondia utilizes a metabolic approach, taking into account the pharmacological mode of action.
Skondia's Nootropic Criteria:
I. No direct vasoactivity
A. No vasodilation
B. No vasoconstriction
II. EEG activity: No change in basic rhythm
A. Quantitative EEG: Increased power spectrum (beta 2 and alpha)
B. Qualitative EEG: Decreased delta waves and cerebral suffering
III. Must pass blood-brain barrier
A. Under normal conditions
B. Under pathological conditions
IV. Must show metabolic activity in:
A. Animal brain metabolism
1. Molecular
2. Physiopathological
B. Human brain metabolism (clinical evaluation)
1. A-V differences
a. Increased extraction quotients of O2
b. Increased extraction quotients of glucose
c. Reduced lactate pyruvate ratio
2. Regional cerebral metabolic rates (rCMR)
a. Increased ICMR of O2
b. Increased rCMR of glucose
3. Regional cerebral blood flow: Normalization
V. Minimal side effects
VI. Clinical trials must be conducted with several rating scales designed to objectify metabolic cerebral improvement.


User was temp banned for this post.
I'm on GOLD CHAIN
ZERG_RUSSIAN
Profile Blog Joined November 2008
10417 Posts
March 19 2013 06:31 GMT
#92
On March 19 2013 13:33 FoxShine wrote:
I have tried piracetam, aniracetam, and oxiracetan. I wanted to get pramiracetam as it is much more potent, iv been unable to find a source for bulk powder. I paired them all with a Choline supplement... One thing i definitely noticed is my short term memory was much better.. I also found it a bit easier to think about things as if my thoughts were clearer. I'm guessing this is the "brain-fog" its supposed to help with. Aniracetam seemed to give me more typos.. don't know what that's about. I know that Pramiracetam and phenyl-piracetam are the most potent of the racetams.. and β-Phenyl-γ-aminobutyric acid (phenibut) is pretty powerful.. For anyone looking to try them i reccomend a choline supplement because it seems to be more effective or atleast synergistic with the lesser racetams. -researched a few years ago information could be slightly inaccurate.

This post has a lot of good stuff in it, if you want a TL;DR for the whole thread look here
I'm on GOLD CHAIN
Manit0u
Profile Blog Joined August 2004
Poland17238 Posts
March 19 2013 07:13 GMT
#93
On March 10 2013 12:48 Cyro wrote:
Show nested quote +
Side Effects:

Show nested quote +
Arousal


Yay sc2 and sex parties :D :D


Why SC2? Studies show that if you're good at the game your thought process is practically turned off when you're playing SC. I'm not sure that this kinds of drugs would help you out.



Also, do you really need more drugs?

Time is precious. Waste it wisely.
HeavenS
Profile Joined August 2004
Colombia2259 Posts
March 19 2013 07:17 GMT
#94
On March 19 2013 10:39 calgar wrote:
Show nested quote +
On March 19 2013 09:43 ShcShc wrote:
On March 12 2013 07:50 JackDT wrote:
Oh boy Dave Asprey. He sells a ton of products and his methods for evaulating scientific evidence are atrocious. I cringe every time he brags on his blog about how many studies on subject X he read. Some examples of things he's selling:

Special coffee that isn't contaminated with toxins like all the other coffee you might drink.

Vibration plates to 'detox your immune system' http://www.bulletproofexec.com/bulletproof-vibe-whole-body-vibration-plate/

An "Earthing" Mat which grounds the body and he insists cures jet lag. http://www.upgradedself.com/tech/earthing-mat.html



No idea about the vibration or earthing. Sounds/looks gimmicky crap.
But his coffee is, honestly, the best.


What 'toxins' are absent that make it more expensive than Starbucks brand (or any other reputable brand)? Do you know that it's not just repackaged folgers? Everything else on the site screams scam so I'm going to guess the coffee is extremely plain and just overpriced. A fool and his money are soon parted, as the saying goes.


this. as a colombian, i can tell you, just invest in a good colombian coffee. you will never look back.
Im cooler than the other side of the pillow.
BrTarolg
Profile Blog Joined June 2009
United Kingdom3574 Posts
March 19 2013 09:15 GMT
#95
Modalert definitely is NOT a placebo, and adderall even more so (amphetamines are NOT placebo's lol)

Though, what you get out of it is up to you. I totally agree that a good diet + sleep + health is the biggest factor. Keeping your brain clear and awake is only one part of the puzzle
Kickboxer
Profile Blog Joined November 2010
Slovenia1308 Posts
March 19 2013 09:25 GMT
#96
Back in my day people just used cocaine.
xContagion
Profile Joined July 2012
United States40 Posts
March 19 2013 12:52 GMT
#97
On March 19 2013 15:30 ZERG_RUSSIAN wrote:

You're retarded, did you even look to see if there was an addiction potential?

There's none btw

User was temp banned for this post.


People become addicted to anything, most addictions are mental.
ShcShc
Profile Joined October 2006
Canada912 Posts
March 19 2013 14:52 GMT
#98
On March 19 2013 18:15 BrTarolg wrote:
Modalert definitely is NOT a placebo, and adderall even more so (amphetamines are NOT placebo's lol)

Though, what you get out of it is up to you. I totally agree that a good diet + sleep + health is the biggest factor. Keeping your brain clear and awake is only one part of the puzzle



Everything should, imo, be taken with moderation.
Modalert would lose on its effect if used daily, but cycle them a week every time at least.

Amphetamines are horrible though. Dependency, known side effects, etc... Should not take it.

God DAJNFBGHSfIDSHUKLFHSGUIO! -Jinro
Epocalypse
Profile Joined December 2011
Canada319 Posts
March 23 2013 18:55 GMT
#99
Tried this combination today: Artichoke Leaf Extract 500mg + Forskolin 10mg ($21.00 + $11.50)
LifeExtension brand for both.

Tim Ferriss said this:
The quest: Think harder.
The drugs: Forskolin (from Coleus forskohlii) and artichoke extract
Where to get it: Online
Benefits: “If you want to go all-natural for enhancing your learning and memory, this duo fits the bill. Bonus: Artichokes contain luteolin, which can inhibit PDE5, which is also how Cialis and other ED drugs work. Who doesn’t want to demolish Sudoku while sporting a massive boner?


This was my first time trying this and it seemed to have absolutely no effect. Neither did it have the pick me up effect that coffee does, but I didn't get a boner either. I'll try again over the next week to see if there is any difference; but given my first experience I don't expect any results.
bw4life
ZackAttack
Profile Joined June 2011
United States884 Posts
March 23 2013 19:16 GMT
#100
On March 10 2013 12:56 FallDownMarigold wrote:
Show nested quote +
On March 10 2013 12:45 Aerisky wrote:
Yeah there doesn't seem to be much info on these and I'm really curious as to what they are, exactly... And yeah, obviously there's the idea of that kind of mental drug's affects... interesting though from what I know, I can't really buy into it.


I can say for certain that from that list of compounds, some of them are fairly well defined. Vasopressin for example, is a naturally occurring substance implicated in things like mood, sexual activity, social activity, etc. One of the things on the list is a drug used in treatment of Parkinson's.

I'm sure all of the things on the list do have effects on the brain, but if they were really that useful for boosting IQ points (lol?) or acting as "brain steroids", I think there would be pretty big incentive for a lot of studies into these effects, which just isn't the case. The spokesman dude says on his site:
Show nested quote +
I blog about how to be a more powerful entrepreneur and human by upgrading your biology at The Bulletproof Executive. I spent 15 years and $250,000 of my own money hacking my biology to gain an unfair advantage in business and life.

I upgraded my brain by >20 IQ points, lost 100lbs, got ripped and became an expert in mental performance, setting my career on fire. My advice has helped hundreds of people upgrade their careers and lives.

...really. Based on that he doesn't appear to know a damn thing about neuroscience, so I would not take advice from the guy on drugs for the brain


Hahaha. If anyone believes this spokesperson based on that, I also have one weird trick to loose weight, aguide on tricking women into sleeping with you, and a secret pill that will add 4 inches to your penis in 4 weeks.
It's better aerodynamics for space. - Artosis
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