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Vladimir is a quite tanky, high sustain AP carry.
Patch history
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v1.0.0.120 - 2011-06-22
Transfusion
Cooldown adjusted to 12/10/8/6/4 from 12/10/8/6/3
Damage adjusted to 90/125/160/195/230 from 70/115/160/205/250
v1.0.0.118b - 2011-05-24
Transfusion heal reduced to 15/25/35/45/55 from 17.5/28.75/40/51.25/62.5
v1.0.0.111 - 2011-02-16
Crimson Pact Bonus ability power gained reduced to 1 ability power per 40 bonus health from 25 health
Sanguine Pool no longer grants a speed bonus on use
Fixed a bug where Turrets would sometimes idle while Vladimir was pooled
Fixed a bug where Sanguine Pool would occasionally not properly draw aggro upon exiting his pool
v1.0.0.110 - 2011-02-01
Sanguine Pool
Slow percentage reduced to 40% from 50%
Slow duration reduced to 1 second from 1.5 seconds
Tides of Blood health cost reduced to 30/40/50/60/70 from 30/45/60/75/90
Fixed a bug where Vladimir would lose health when leveling in some instances
v1.0.0.106 - 2010-12-01
Fixed a bug where Tides of Blood was not providing Vladimir with enough increased regeneration and healing
Fixed a bug where Tides of Blood did not deal full damage if you had 4 stacks before casting
Hemoplague
Cooldown increased to 150/135/120 seconds from 120
Damage amplification effect changed to 14% at all ranks from 10/14/18%
Base damage reduced to 150/250/350 from 200/300/400
Ability power ratio reduced to 0.7 from 0.75
v1.0.0.105 - 2010-11-15
Transfusion will now heal Vladimir even if the target is spell immune
Hemoplague will no longer damage enemies if it is dispelled
V1.0.0.102 - 2010-10-04
Sanguine Pool
Duration reduced to 2 seconds from 2.5
Slow duration increased to 1.5 seconds from 1 second
Damage per second changed to 20/33.75/47.5/61.25/75 retaining the same overall damage
Fixed a bug where Sanguine Pool wasn't dealing enough damage
v1.0.0.101 - 2010-09-21
Fixed a bug where Transfusion was not restoring enough health from Spell Vamp (not how much the spell heals normally)
Fixed a bug where Transfusion's tooltip showed it restoring less health than it did
Crimson Pact (passive) no longer heals Vladimir when his Ability Power increases
v1.0.0.100 - 2010-09-08
Tweaked volume level of skill sounds
v1.0.0.99 - 2010-08-24
Transfusion cast range reduced to 600 from 650
Tides of Blood buff duration increased to 10 from 8
Tides of Blood cast range increased to 620 from 570
v1.0.0.98 - 2010-08-10
Crimson Pact (passive) tooltip now displays stat bonuses
Sanguine Pool cooldown increased to 26/23/20/17/14 from 25/22/19/16/13
Tides of Blood health cost reduced to 30/45/60/75/90 from 40/55/70/85/100
Tides of Blood is now blocked by spell shield.
Transfusion
Cooldown adjusted to 12/10/8/6/4 from 12/10/8/6/3
Damage adjusted to 90/125/160/195/230 from 70/115/160/205/250
v1.0.0.118b - 2011-05-24
Transfusion heal reduced to 15/25/35/45/55 from 17.5/28.75/40/51.25/62.5
v1.0.0.111 - 2011-02-16
Crimson Pact Bonus ability power gained reduced to 1 ability power per 40 bonus health from 25 health
Sanguine Pool no longer grants a speed bonus on use
Fixed a bug where Turrets would sometimes idle while Vladimir was pooled
Fixed a bug where Sanguine Pool would occasionally not properly draw aggro upon exiting his pool
v1.0.0.110 - 2011-02-01
Sanguine Pool
Slow percentage reduced to 40% from 50%
Slow duration reduced to 1 second from 1.5 seconds
Tides of Blood health cost reduced to 30/40/50/60/70 from 30/45/60/75/90
Fixed a bug where Vladimir would lose health when leveling in some instances
v1.0.0.106 - 2010-12-01
Fixed a bug where Tides of Blood was not providing Vladimir with enough increased regeneration and healing
Fixed a bug where Tides of Blood did not deal full damage if you had 4 stacks before casting
Hemoplague
Cooldown increased to 150/135/120 seconds from 120
Damage amplification effect changed to 14% at all ranks from 10/14/18%
Base damage reduced to 150/250/350 from 200/300/400
Ability power ratio reduced to 0.7 from 0.75
v1.0.0.105 - 2010-11-15
Transfusion will now heal Vladimir even if the target is spell immune
Hemoplague will no longer damage enemies if it is dispelled
V1.0.0.102 - 2010-10-04
Sanguine Pool
Duration reduced to 2 seconds from 2.5
Slow duration increased to 1.5 seconds from 1 second
Damage per second changed to 20/33.75/47.5/61.25/75 retaining the same overall damage
Fixed a bug where Sanguine Pool wasn't dealing enough damage
v1.0.0.101 - 2010-09-21
Fixed a bug where Transfusion was not restoring enough health from Spell Vamp (not how much the spell heals normally)
Fixed a bug where Transfusion's tooltip showed it restoring less health than it did
Crimson Pact (passive) no longer heals Vladimir when his Ability Power increases
v1.0.0.100 - 2010-09-08
Tweaked volume level of skill sounds
v1.0.0.99 - 2010-08-24
Transfusion cast range reduced to 600 from 650
Tides of Blood buff duration increased to 10 from 8
Tides of Blood cast range increased to 620 from 570
v1.0.0.98 - 2010-08-10
Crimson Pact (passive) tooltip now displays stat bonuses
Sanguine Pool cooldown increased to 26/23/20/17/14 from 25/22/19/16/13
Tides of Blood health cost reduced to 30/45/60/75/90 from 40/55/70/85/100
Tides of Blood is now blocked by spell shield.
How to use your skills
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Passive:Gives you very high hitpoint values while still building pure AP. However, you will lack resistances so you're really not a tank but you can tank 1-2 people pretty well if you consider your high HP and your absurd selfheal.
Q:Your main spell, use it to lasthit/harass in laning phase and just spam it in fights. Very bad at level 1 but becomes really great at level 5.
W:Mainly used as an escape spell. Keep in mind DoTs and non-target AoEs still hit you while in your pool. Also it costs a quite high percentage of your life so use it carefully. You pretty much only want to use it offensively for the slow if youre chasing someone and you're safe yourself. Even if you use it defensive don't just pool at everything that comes near you. Your pool has quite a high cooldown and if you wasted it for something not worth pooling, you are often fucked. Only use if you really have to.
E:Your main farming tool, use it lasthit tricky minions in laning phase, if you can and use it to farm/push when needed. It stacks even if it hits nobody, so you can always stack up to 4 stacks before a fight begins.
R:Your AoE ult. Use it early so your team benefits from the damage amplifier. Use it in laning phase to finish someone off during ganks or fights. You should save it for teamfights later on, as you NEED it for teamfights.
Summoner Spells
Flash + Heal
Flash is a must, it's still really good, especially to avoid ganks and stuff like that. Heal is really fucking strong since the summoners changes, it heals for STUPID amounts on Vlad. I've also seen some people go Heal/Ignite which seems like an all out laning setup.
Masteries
21/9/0 seems really strong, especially when you run Heal. But I've also seen people run 21/0/9 or even 21 in defense.
Runes:
Reds: mpen
Yellows: flat armor/mr OR hp/level OR ap/level
Blues: flat magicresist OR flat cdr
Quints: flat ap OR spellvamp OR movementspeed
Magic penetration in reds is obvious for casters. In yellows you can either take flat armor/mr to help your laning or hp/level or ap/level which is better in mid/lategame. In blues you can either take flat mr if you need the mr to survive your lane or flat CDR. In quints there's multiple options but I've mostly seen flat ap or spellvamp. Movementspeed is really good later on but lacks laning power.
Skill Order
QWQEQR, R > Q > E > W
Obviously Q is your bread and butter, max it first. E is good farm and decent AoE damage, so max it next. W is a nice one point wonder. You can take W at level 1 for a level 1 teamfights/gank.
Items
Valuable items for Vlad
Will Of The Ancients
CDR boots
Deathcap
Rylais
Zhonyas
Voidstaff
In depth item guide
You pretty much always want to start with boots and 3 potion, it's the best opening for surviving those early levels as the mobility from boots is much needed. Your first item will always be a Will Of The Ancients for the sustain. Deathcap is obviously a core item so you will get it as soon as possible. In terms of boots you want CDR unless the enemy team has like 10 stuns for some reason. Shove those level2 boots in when you have 700g to spare and nothing else to buy, the 15% CDR aren't that big of a deal in earlygame but you'll want it in midgame. After Deathcap, Rylais or Zhonyas are the options. You generally go for Rylais first unless the enemy team has a lot of AD or you need the active really bad. Go for the one you haven't bought yet after. Force Of Nature is a situational item. If the enemy team has a lot of AP you can get it get it rather early. Otherwise if you need more magicresist lategame you can always get FoN over Zhonyas-
Note: If you have trouble surviving in mid/lategame buying a negatron/chainmail (depending on the enemy team, of course) is always a really good way to instantly raise your effective HP immensly. You can always delay the FoN/Zhonyas until later.
Spirit Visage can be a cheap and effective item in some cases where need some cheap early defense.
Laning
These days people seem to prefer to run Vlad top where he can dominate a lot of meeles. Run an agressive setup an shove those Qs in their face. Mid seems harder since a lot of common APs can dominate Vlad early.
Farming
Vlad is a rather passive carry, not like someone like Annie. Farming is your top priority and you should pretty much only enter teamfights with your ult up, which you should generally start using carefully from level 11 on or so. Vlad in a teamfight without his ult is pretty much useless. Farming waves with QE is really fast and you'll never run out of HP past level 9 so keep your eyes open for farming opportunuties around the map.
Teamfights
There are pretty much only two important things. One, get your ult off on as many people as possible and rather early, so your team benifit from the damage amplifier. Two, DONT GET BURSTED FOR GODS SAKE. As Vlad you win games by surviving the initial burst, being unkillable and cleaning everything up at a reasonable rate. Of course you have your pool and flash for screwups, but those cant always save you from a bad position and it's always good to have them saved up.
enjoy~