Although reflective symmetry is a little weird in 1v1 maps, in 2v2 it enables varied strategy in relation to spawn positions without inherent positional imbalance. Lost temple, Metalopolis, Shakuras plateau, all the poplar 2v2 maps have bi-axial, reflective symmetry.
So rotation for 1v1, reflection for 2v2. Although it's all about the 1v1 play, so why bother making 2v2 maps? Big, rotational 1v1s with lots of expansions are the way forward imo.