On April 03 2011 08:37 Froadac wrote: My mom's a pharmacist. they can synthesize most cannaboids.
also why go the chemical way when nature makes that stuff grow in your garden?
Because THC =\= cannabis. Cannabis has many more carcinogens than cigarettes.
The only real defense of this is THC counteracts the carcinogens, but there are studies that have discounted that as statistical error and found lung cancer risk. I guess you could also say volume of marijuana smoked over a lifetime is likely much lower than a tobacco smoker.
Please don't use the, "Its natural!" defense. Arsenic is natural. Poison ivy is natural. Everything is natural. Just think about it. I don't really care about marijuana either way, but the natural thing just gets on my nerves.
I believe a lot of the conclusions being drawn from the NCI excerpt are misinformed. Cannabinoids are a pretty diverse range of chemicals and their effects are just as diverse and poorly understood.
It's difficult to interpret data being extrapolated from clinical trials even for PhD/MDs so I would hardly think that the average person (regardless of intelligence) is qualified to make any sort of educated statements about it.
I've worked in the pharma/biotech industry for 5 years (strategy consulting, CRO, currently as a sales manager) and my education is in neurobiology and I still glaze over when reading clinical trial data. And I've read my share.
Drano is anti-tumor in that if culture some cancerous cells and pour Drano on it, they will die. Anti-cancer compound. Should you drink Drano if you have cancer?
This trial proves effectively one thing: cannibinoids are toxic to certain cells. Not groundbreaking or justification for anything.
On April 03 2011 07:27 Silmakuoppaanikinko wrote: that MJ has been linked to triggering a psychosis or paranoid episodes in people who are sensitive for it, that's also hard to deny.
marijuana in high doses does cause acute psychosis along with numerous other drugs
lol no, no it doesn't
*may cause* could be accurate, though that's not proved.
On April 03 2011 08:28 chonkyfire wrote: Do you know how the studies come the conclusion marijuana causes psychosis? It's because they inject massive amounts of THC without any of cannabinoids and the person who receives the THC express symptoms of psychosis.
What studies are you refering to specifically? Most stuides i've encountered involving humans are case studies which work with people who smoke the drug, i would be interested to learn of a study which injected large amounts of thc into a human.
There's tons.
The reason for doing it is because marijuana contains lots of different cannabinoids, so they will inject THC alone and then THC with others such as CBD and CBN, and compare the effects.
As much as I would like to trust my fellow TLer, I would still like too see a few of those studies. Im searching now but am having trouble finding one which injected patients with large amounts of thc, the ethics and methodology behind such a study would be very interesting to me. Please provide me with one.
I think I'm wording this wrongly. Let's start by saying there's so many studies claiming cannabis causes psychosis is because people who abuse cannabis often exhibit behaviors that closely resemble psychosis such a hallucinations, paranoia and possibly delusions. People who are heavily intoxicated will also often have trouble continuing a train of thought or say things that sometimes will make no sense.
You may have seen this video, but they will inject her with pure THC and THC/CBD. It's already been pretty well known that the other cannabinoids in marijuana play a pretty big role in the actual "high" of marijuana. CBD specifically is considered an antipsychotic with anxiolytic effects.
On April 03 2011 08:52 GloPikkle wrote: I believe a lot of the conclusions being drawn from the NCI excerpt are misinformed. Cannabinoids are a pretty diverse range of chemicals and their effects are just as diverse and poorly understood.
Very well said, and it should be noted that many "commercial" strains of cannabis has bred most if not all of the CBDs out of the plant whenever possible because those chemicals go hand-in-hand with the couchlock/burned out feelings.
That said, a breeder in California has produced a strain of cannabis with more CBD than THC, (~10% CBD levels). It's very exciting for people who want to don't want to pump their bodies full of chemicals produced in a lab. Obviously eating cannabis and/or the various extracts isn't going to be for everyone.
On April 03 2011 08:07 Whitewing wrote: The reason cannabis is still illegal is an economic one, it has nothing to actually do with the substance.
A lot of jobs only exist because cannabis is illegal. The fact that those jobs shouldn't exist and cannabis should be legal isn't really considered.
Not really. What kind of jobs would dissapear if MJ would be legalized ? Besides traffickers there really isn't any? Nearly all MJ related law enforcement could just be given an actual useful job. like hunting real criminal, those that actually hurt other ppl.
MJ is illegal because powerful lobbies want it to be. Paper, textile and petrol industry lobby would all lose allot of money if it was fully legalized. That's why it got outlawed in the first place. Did you know that before WW2 hemp was the 2nd cash crop in the US?
On April 03 2011 08:52 GloPikkle wrote: I believe a lot of the conclusions being drawn from the NCI excerpt are misinformed. Cannabinoids are a pretty diverse range of chemicals and their effects are just as diverse and poorly understood.
That said, a breeder in California has produced a strain of cannabis with more CBD than THC, (~10% CBD levels). It's very exciting for people who want to don't want to pump their bodies full of chemicals produced in a lab. Obviously eating cannabis and/or the various extracts isn't going to be for everyone.
Do you know what it's called? It's proven 10%? I"ve heard of 2%, but 10 is pretty crazy
On April 03 2011 08:52 GloPikkle wrote: I believe a lot of the conclusions being drawn from the NCI excerpt are misinformed. Cannabinoids are a pretty diverse range of chemicals and their effects are just as diverse and poorly understood.
That said, a breeder in California has produced a strain of cannabis with more CBD than THC, (~10% CBD levels). It's very exciting for people who want to don't want to pump their bodies full of chemicals produced in a lab. Obviously eating cannabis and/or the various extracts isn't going to be for everyone.
Do you know what it's called? It's proven 10%? I"ve heard of 2%, but 10 is pretty crazy
I want to smoke some of that
LOL.. wait guys. you have some SERIOUS misunderstandings please let me clarify.
a high CBD amount isnt anything special at all. first of all, CBD isnt psychoactive. it is said that it still alters the THC high. but it's not psychoactive itself.
secondly... as a rule of thumb, the less THC a plant has, the more CBD it has. REALLY. it works this way .
CBD is nothing special
2% cbd means, that the plant has quite some THC. 10% cbd plants would probably be <10% thc. nothing special whatsoever. every plant with low THC will have high CBD. EVERY. in germany there's plants with 0.2% THC... they have A LOT OF CBD though!
On April 03 2011 08:52 GloPikkle wrote: I believe a lot of the conclusions being drawn from the NCI excerpt are misinformed. Cannabinoids are a pretty diverse range of chemicals and their effects are just as diverse and poorly understood.
That said, a breeder in California has produced a strain of cannabis with more CBD than THC, (~10% CBD levels). It's very exciting for people who want to don't want to pump their bodies full of chemicals produced in a lab. Obviously eating cannabis and/or the various extracts isn't going to be for everyone.
Do you know what it's called? It's proven 10%? I"ve heard of 2%, but 10 is pretty crazy
I want to smoke some of that
It was tested in a laboratory yes. He calls it Sour Tsunami. A quote from a website,
For the first time, a California grower has "stabilized" a Cannabis strain high in Cannabidiol. Lawrence Ringo of the Southern Humboldt Seed Collective is now offering seeds of "Sour Tsunami" that have a one-in-four chance of containing 10-11% CBD (and 6-7% THC)!
On April 03 2011 08:37 Froadac wrote: My mom's a pharmacist. they can synthesize most cannaboids.
also why go the chemical way when nature makes that stuff grow in your garden?
Because THC =\= cannabis. Cannabis has many more carcinogens than cigarettes.
The only real defense of this is THC counteracts the carcinogens, but there are studies that have discounted that as statistical error and found lung cancer risk. I guess you could also say volume of marijuana smoked over a lifetime is likely much lower than a tobacco smoker.
Please don't use the, "Its natural!" defense. Arsenic is natural. Poison ivy is natural. Everything is natural. Just think about it. I don't really care about marijuana either way, but the natural thing just gets on my nerves.
if you read the rest of my post you quoted youll see why im against this synthetic stuff.it wasnt some "defense" in any way. but when i have to pick between untested synthetic expensive stuff and the normal kind that millions of people have "tested" for years then imho the choice isnt hard
also you dont have to smoke at all. vaporizers and eating/drinking are all fine alternatives.
On April 03 2011 08:52 GloPikkle wrote: I believe a lot of the conclusions being drawn from the NCI excerpt are misinformed. Cannabinoids are a pretty diverse range of chemicals and their effects are just as diverse and poorly understood.
That said, a breeder in California has produced a strain of cannabis with more CBD than THC, (~10% CBD levels). It's very exciting for people who want to don't want to pump their bodies full of chemicals produced in a lab. Obviously eating cannabis and/or the various extracts isn't going to be for everyone.
Do you know what it's called? It's proven 10%? I"ve heard of 2%, but 10 is pretty crazy
I want to smoke some of that
LOL.. wait guys. you have some SERIOUS misunderstandings please let me clarify.
a high CBD amount isnt anything special at all. first of all, CBD isnt psychoactive. it is said that it still alters the THC high. but it's not psychoactive itself.
secondly... as a rule of thumb, the less THC a plant has, the more CBD it has. REALLY. it works this way .
CBD is nothing special
2% cbd means, that the plant has quite some THC. 10% cbd plants would probably be <10% thc. nothing special whatsoever. every plant with low THC will have high CBD. EVERY. in germany there's plants with 0.2% THC... they have A LOT OF CBD though!
Yes but it still has effects on the cannabinoid receptors. There is evidence that CBD is also a 5Ht agonist
CBD also apparently binds to another cannabinoid besides CB1/CB2 that is called GPR55, which we don't know too much about. There is no denying though that CBD produces unique effects.
People are using pretty bold words here considering the scope of actual and legit data on cannabinoids compared to eg. a three phase drug trial. I'd be careful of drawing conclusions from numerous dispersed and non-standardized datasets.
Having said that, I sincerely hope the_important_people put a stop to cannabinoid research marginalization and we get those large, legit, standardized and reviewed datasets. At the current state of affairs I'd say it's hard for a government to say it has the best interests of its citizens in mind when it ices cannabinoid research funding and allocates exorbitant funds to anti-drug law enforcement.
[QUOTE]On April 03 2011 09:05 Nizaris wrote: [QUOTE]On April 03 2011 08:07 Whitewing wrote: The reason cannabis is still illegal is an economic one, it has nothing to actually do with the substance.
MJ is illegal because powerful lobbies want it to be. Paper, textile and petrol industry lobby would all lose allot of money if it was fully legalized. That's why it got outlawed in the first place. Did you know that before WW2 hemp was the 2nd cash crop in the US?[/QUOTE] +1
On April 03 2011 07:26 bRuTaL!! wrote: What about schizophrenia? If its cancer your concerned about, eat "super" foods...
I believe that MJ has been linked to triggering a psychosis or paranoid episodes in people who are sensitive for it, that's also hard to deny.
It also can exacerbate existing anxiety issues. Nearly everyone I know who quit did it to avoid the feelings of paranoia, anxiety, and laziness that results from using it often.
On April 03 2011 07:55 Teivospy wrote: they really do need to legalize marijuana though, its getting ridiculous how much money is spent to control something that isn't being controlled
that said if you do use any drug you are likely a total moron and I hope you OD at some point in your life off being depressed that you were too stoned to do anything in your life
EPT
please let me clarify.
