I play Protoss, I'm using custom hotkeys (close to grid hotkeys), hotkey gateways and produce armies predominantly off hotkeys alone as well as camera hotkeys on bases (F2 - F4) , watching Pro replays and when it shows their hot keys in real time, they always hot keys workers or larva in early game, seems like the only reason for this is to spam HK(hotkey)1 and HK2 and they hit 300-400 APM, does this transition to army hotkeys mid to late game and they are just spamming HKs 1/2/3/ etc maintaining high APMS
So considering the above, if you were to take out spamming HKs would their APM drop to 150-250~ which i can realistically see myself reaching about 200~, to me i can;t see how anything above 300 is possible without spamming useless hotkeys that doesn't add any value into the game, aside from high APM