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Any and all updates regarding the COVID-19 will need a source provided. Please do your part in helping us to keep this thread maintainable and under control.
It is YOUR responsibility to fully read through the sources that you link, and you MUST provide a brief summary explaining what the source is about. Do not expect other people to do the work for you.
Conspiracy theories and fear mongering will absolutely not be tolerated in this thread. Expect harsh mod actions if you try to incite fear needlessly.
This is not a politics thread! You are allowed to post information regarding politics if it's related to the coronavirus, but do NOT discuss politics in here.
Added a disclaimer on page 662. Many need to post better. |
On November 05 2021 23:38 teeel141 wrote:Show nested quote +On November 05 2021 23:05 ChristianS wrote:Not sure if you’re just trolling, but here’s PF-07321332 (Pfizer’s new drug, Paxlovid is just this plus ritonavir): WikipediaAnd here’s Ivermectin: WikipediaAs you can see they’re totally different structures. So, yes, it’s unsurprising they perform differently in the clinic. Completely different drugs often do. Ivermectin has been proven to be a protease inhibitor in a lab or so i've read. So it's the same mechanism of action.
Can you link the study showing its effectiveness in treating covid?
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A highly functional treatment already so soon would be absolutely astonishing. If Paxlovid holds what it promises, it can help give a huge push towards ending the pandemic.
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On November 06 2021 00:57 Magic Powers wrote:
A highly functional treatment already so soon would be absolutely astonishing. If Paxlovid holds what it promises, it can help give a huge push towards ending the pandemic.
Yes, that would be nice!
There is a cost/benefit concern with that medication, though. 86% reduction sounds like a lot, in groups where very few need to go to hospital anyway, you might need to medicare several thousand patients to only archive minimal relief for the hospitals.
I don't see how this is "ending", but immunity by infection+vaccines will win out eventually so it is reduced to "one of those diseases".
I highly recommend the recent Kurtzgezagt video series on YouTube about our immune system. It is absolutely mind-blowing!
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On November 05 2021 23:51 JimmiC wrote:Show nested quote +On November 05 2021 23:34 teeel141 wrote:On November 05 2021 23:24 JimmiC wrote:On November 05 2021 23:07 Sermokala wrote:
Its incredible what the difference between medicine that is tested for something and is proven good and medicine that is tested for something and not proven good in the eyes of scientists and the media. The stupid crowd being so obsessed with made up conspiracies. Ivermectin just does not work on covid, it has been tested it sucks. Sorry you were tricked by the same people that think JFK ghost is coming back to fight the deep state but you were. Like why is Merck (who makes ivermectin) not big evil big pharma? What makes them good big pharma? They have 48 billion in revenue. Pfizer he 42 Billion in revenue and like half the stock value. Their is not even a hint of logic to this stupidity. And Merck have an approved covid treatment its called Molnupiravir, and it is getting authorized and used before Pfizers was. Its just Ivermectin was not because that is not what it does. https://www.ctvnews.ca/health/coronavirus/u-k-authorizes-merck-antiviral-pill-1st-shown-to-treat-covid-19-1.5651764This crowd is basically mad that Antivan is not being prescribed for erectile disfunction without realizing that Viagra is and unlike Anitvan it actually helps with ED. Ivermectin is a generic drug and anybody can make it. There's no profit in it. I can't believe people still bring up Merck as some argument. Because Merck developed it and is still a major manufacturer of it? The same wait there is Generic Viagra and Pfizer is a major manufacturer of it...... And it is just stupidity at this point that it is talked about around covid, it does not work. Show nested quote +On Oct. 11 drug company Merck applied for emergency use authorization from the FDA for its COVID-19 pill called 'Molnupiravir;' it is not the same as Ivermectin. Show nested quote +They’re chemically different, meaning the structure of the molecules is not the same. According to the National Center for Biotechnology Information, a department within the National Institutes of Health's National Library of Medicine, the two have very different chemical structures. Ivermectin's formula is C48H74O14, while Molnupiravir's is C13H19N3O7
The organism they attack is different. Ivermectin attacks parasites. While the new Merck drug attacks RNA viruses.
They attack each organism differently. Ivermectin ruptures the cell membrane, which paralyzes and kills the parasite. While Molnupiravir corrupts the mRNA inside the cell, preventing the virus from replicating effectively.. The drugs are used to treat two completely different conditions. Ivermectin treats conditions caused by certain parasites. It's approved orally to treat intestinal strongyloidiasis and onchocerciasis (also known as river blindness) and topically to treat head lice and rosacea. Molnupiravir, on the other hand, is being studied to treat COVID-19. Right now, there is no evidence that Ivermectin treats COVID-19.
https://www.wusa9.com/article/news/verify/no-mercks-covid19-pill-molnupiravir-is-not-the-same-as-ivermectin-fact-check/65-60411c26-f515-4cbc-a955-fafd42d78780I Show nested quote +vermectin has been pushed by right-wing politicians and activists promoting it as a supposed COVID treatment.[83][84][85] Misinformation about ivermectin's efficacy spread widely on social media, fueled by publications that have since been retracted,[86][87] misleading "meta-analysis" websites with substandard methods,[88][89] and conspiracy theories about efforts by governments and scientists to "suppress the evidence."[90][91]
In response to widespread misuse, the U.S. Food and Drug Administration, U.S. Centers for Disease Control, World Health Organization, American Medical Association, American Pharmacists Association, and American Society of Health-System Pharmacists issued statements in 2021 warning that ivermectin is not approved or authorized for the treatment or prevention of COVID-19, and advised against its use for that purpose outside of clinical trials.[60][22][92]
On September 1, 2021, health experts from the United States expressed concerns from reports of sharp increases in outpatient prescribing and dispensing of ivermectin with respect to levels before the pandemic.[93] These experts explain that the CDC has not authorized or approved ivermectin for the prevention or treatment of COVID-19. The American Association of Poison Control Centers has reported 1,440 cases of ivermectin poisoning through September 20, 2021, a three-fold increase compared to similar time periods in 2019 and 2020.[94] https://en.wikipedia.org/wiki/IvermectinShow nested quote +On November 05 2021 23:38 teeel141 wrote:On November 05 2021 23:05 ChristianS wrote:Not sure if you’re just trolling, but here’s PF-07321332 (Pfizer’s new drug, Paxlovid is just this plus ritonavir): WikipediaAnd here’s Ivermectin: WikipediaAs you can see they’re totally different structures. So, yes, it’s unsurprising they perform differently in the clinic. Completely different drugs often do. Ivermectin has been proven to be a protease inhibitor in a lab or so i've read. So it's the same mechanism of action. Post where you read it.
I suspect he found it in the same place Reuters found it and posted this fact check of it:
https://www.google.com/amp/s/mobile.reuters.com/article/amp/idUSL1N2R11T5
Conclusion: they definitely don't work the same way. Although it's possible (although there is no evidence so far whatsoever that it even works at all) that Ivermectin combats Covid in a similar way, Ivermectin has multiple effects, some of which are potentially dangerous for humans, so even in the best case that Ivermectin does actually work to combat Covid (once again, no evidence so far), it may have worse side effects. The medicine Pfizer developed may also have side effects, but it is designed to specifically target a protease used in critical processes by the SARS-CoV-2 virus, and that hopefully limits unwanted and dangerous side effects.
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On November 06 2021 03:35 Acrofales wrote:Show nested quote +On November 05 2021 23:51 JimmiC wrote:On November 05 2021 23:34 teeel141 wrote:On November 05 2021 23:24 JimmiC wrote:On November 05 2021 23:07 Sermokala wrote:
Its incredible what the difference between medicine that is tested for something and is proven good and medicine that is tested for something and not proven good in the eyes of scientists and the media. The stupid crowd being so obsessed with made up conspiracies. Ivermectin just does not work on covid, it has been tested it sucks. Sorry you were tricked by the same people that think JFK ghost is coming back to fight the deep state but you were. Like why is Merck (who makes ivermectin) not big evil big pharma? What makes them good big pharma? They have 48 billion in revenue. Pfizer he 42 Billion in revenue and like half the stock value. Their is not even a hint of logic to this stupidity. And Merck have an approved covid treatment its called Molnupiravir, and it is getting authorized and used before Pfizers was. Its just Ivermectin was not because that is not what it does. https://www.ctvnews.ca/health/coronavirus/u-k-authorizes-merck-antiviral-pill-1st-shown-to-treat-covid-19-1.5651764This crowd is basically mad that Antivan is not being prescribed for erectile disfunction without realizing that Viagra is and unlike Anitvan it actually helps with ED. Ivermectin is a generic drug and anybody can make it. There's no profit in it. I can't believe people still bring up Merck as some argument. Because Merck developed it and is still a major manufacturer of it? The same wait there is Generic Viagra and Pfizer is a major manufacturer of it...... And it is just stupidity at this point that it is talked about around covid, it does not work. On Oct. 11 drug company Merck applied for emergency use authorization from the FDA for its COVID-19 pill called 'Molnupiravir;' it is not the same as Ivermectin. They’re chemically different, meaning the structure of the molecules is not the same. According to the National Center for Biotechnology Information, a department within the National Institutes of Health's National Library of Medicine, the two have very different chemical structures. Ivermectin's formula is C48H74O14, while Molnupiravir's is C13H19N3O7
The organism they attack is different. Ivermectin attacks parasites. While the new Merck drug attacks RNA viruses.
They attack each organism differently. Ivermectin ruptures the cell membrane, which paralyzes and kills the parasite. While Molnupiravir corrupts the mRNA inside the cell, preventing the virus from replicating effectively.. The drugs are used to treat two completely different conditions. Ivermectin treats conditions caused by certain parasites. It's approved orally to treat intestinal strongyloidiasis and onchocerciasis (also known as river blindness) and topically to treat head lice and rosacea. Molnupiravir, on the other hand, is being studied to treat COVID-19. Right now, there is no evidence that Ivermectin treats COVID-19.
https://www.wusa9.com/article/news/verify/no-mercks-covid19-pill-molnupiravir-is-not-the-same-as-ivermectin-fact-check/65-60411c26-f515-4cbc-a955-fafd42d78780I vermectin has been pushed by right-wing politicians and activists promoting it as a supposed COVID treatment.[83][84][85] Misinformation about ivermectin's efficacy spread widely on social media, fueled by publications that have since been retracted,[86][87] misleading "meta-analysis" websites with substandard methods,[88][89] and conspiracy theories about efforts by governments and scientists to "suppress the evidence."[90][91]
In response to widespread misuse, the U.S. Food and Drug Administration, U.S. Centers for Disease Control, World Health Organization, American Medical Association, American Pharmacists Association, and American Society of Health-System Pharmacists issued statements in 2021 warning that ivermectin is not approved or authorized for the treatment or prevention of COVID-19, and advised against its use for that purpose outside of clinical trials.[60][22][92]
On September 1, 2021, health experts from the United States expressed concerns from reports of sharp increases in outpatient prescribing and dispensing of ivermectin with respect to levels before the pandemic.[93] These experts explain that the CDC has not authorized or approved ivermectin for the prevention or treatment of COVID-19. The American Association of Poison Control Centers has reported 1,440 cases of ivermectin poisoning through September 20, 2021, a three-fold increase compared to similar time periods in 2019 and 2020.[94] https://en.wikipedia.org/wiki/IvermectinOn November 05 2021 23:38 teeel141 wrote:On November 05 2021 23:05 ChristianS wrote:Not sure if you’re just trolling, but here’s PF-07321332 (Pfizer’s new drug, Paxlovid is just this plus ritonavir): WikipediaAnd here’s Ivermectin: WikipediaAs you can see they’re totally different structures. So, yes, it’s unsurprising they perform differently in the clinic. Completely different drugs often do. Ivermectin has been proven to be a protease inhibitor in a lab or so i've read. So it's the same mechanism of action. Post where you read it. I suspect he found it in the same place Reuters found it and posted this fact check of it: https://www.google.com/amp/s/mobile.reuters.com/article/amp/idUSL1N2R11T5Conclusion: they definitely don't work the same way. Although it's possible (although there is no evidence so far whatsoever that it even works at all) that Ivermectin combats Covid in a similar way, Ivermectin has multiple effects, some of which are potentially dangerous for humans, so even in the best case that Ivermectin does actually work to combat Covid (once again, no evidence so far), it may have worse side effects. The medicine Pfizer developed may also have side effects, but it is designed to specifically target a protease used in critical processes by the SARS-CoV-2 virus, and that hopefully limits unwanted and dangerous side effects.
I remember reading it in a different fact check article and it admitted some in vitro study showed it. I just don't remember the article exactly and i never looked for the study.
If you are talking about neurological side effects from ivermectin then you should know that ivermectin doesn't cross the blood brain barrier.
Also i love how your fact check article uses Pfizer spokeperson as a source, very thrustworthy!
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Northern Ireland27265 Posts
On November 06 2021 04:45 teeel141 wrote:Show nested quote +On November 06 2021 03:35 Acrofales wrote:On November 05 2021 23:51 JimmiC wrote:On November 05 2021 23:34 teeel141 wrote:On November 05 2021 23:24 JimmiC wrote:On November 05 2021 23:07 Sermokala wrote:
Its incredible what the difference between medicine that is tested for something and is proven good and medicine that is tested for something and not proven good in the eyes of scientists and the media. The stupid crowd being so obsessed with made up conspiracies. Ivermectin just does not work on covid, it has been tested it sucks. Sorry you were tricked by the same people that think JFK ghost is coming back to fight the deep state but you were. Like why is Merck (who makes ivermectin) not big evil big pharma? What makes them good big pharma? They have 48 billion in revenue. Pfizer he 42 Billion in revenue and like half the stock value. Their is not even a hint of logic to this stupidity. And Merck have an approved covid treatment its called Molnupiravir, and it is getting authorized and used before Pfizers was. Its just Ivermectin was not because that is not what it does. https://www.ctvnews.ca/health/coronavirus/u-k-authorizes-merck-antiviral-pill-1st-shown-to-treat-covid-19-1.5651764This crowd is basically mad that Antivan is not being prescribed for erectile disfunction without realizing that Viagra is and unlike Anitvan it actually helps with ED. Ivermectin is a generic drug and anybody can make it. There's no profit in it. I can't believe people still bring up Merck as some argument. Because Merck developed it and is still a major manufacturer of it? The same wait there is Generic Viagra and Pfizer is a major manufacturer of it...... And it is just stupidity at this point that it is talked about around covid, it does not work. On Oct. 11 drug company Merck applied for emergency use authorization from the FDA for its COVID-19 pill called 'Molnupiravir;' it is not the same as Ivermectin. They’re chemically different, meaning the structure of the molecules is not the same. According to the National Center for Biotechnology Information, a department within the National Institutes of Health's National Library of Medicine, the two have very different chemical structures. Ivermectin's formula is C48H74O14, while Molnupiravir's is C13H19N3O7
The organism they attack is different. Ivermectin attacks parasites. While the new Merck drug attacks RNA viruses.
They attack each organism differently. Ivermectin ruptures the cell membrane, which paralyzes and kills the parasite. While Molnupiravir corrupts the mRNA inside the cell, preventing the virus from replicating effectively.. The drugs are used to treat two completely different conditions. Ivermectin treats conditions caused by certain parasites. It's approved orally to treat intestinal strongyloidiasis and onchocerciasis (also known as river blindness) and topically to treat head lice and rosacea. Molnupiravir, on the other hand, is being studied to treat COVID-19. Right now, there is no evidence that Ivermectin treats COVID-19.
https://www.wusa9.com/article/news/verify/no-mercks-covid19-pill-molnupiravir-is-not-the-same-as-ivermectin-fact-check/65-60411c26-f515-4cbc-a955-fafd42d78780I vermectin has been pushed by right-wing politicians and activists promoting it as a supposed COVID treatment.[83][84][85] Misinformation about ivermectin's efficacy spread widely on social media, fueled by publications that have since been retracted,[86][87] misleading "meta-analysis" websites with substandard methods,[88][89] and conspiracy theories about efforts by governments and scientists to "suppress the evidence."[90][91]
In response to widespread misuse, the U.S. Food and Drug Administration, U.S. Centers for Disease Control, World Health Organization, American Medical Association, American Pharmacists Association, and American Society of Health-System Pharmacists issued statements in 2021 warning that ivermectin is not approved or authorized for the treatment or prevention of COVID-19, and advised against its use for that purpose outside of clinical trials.[60][22][92]
On September 1, 2021, health experts from the United States expressed concerns from reports of sharp increases in outpatient prescribing and dispensing of ivermectin with respect to levels before the pandemic.[93] These experts explain that the CDC has not authorized or approved ivermectin for the prevention or treatment of COVID-19. The American Association of Poison Control Centers has reported 1,440 cases of ivermectin poisoning through September 20, 2021, a three-fold increase compared to similar time periods in 2019 and 2020.[94] https://en.wikipedia.org/wiki/IvermectinOn November 05 2021 23:38 teeel141 wrote:On November 05 2021 23:05 ChristianS wrote:Not sure if you’re just trolling, but here’s PF-07321332 (Pfizer’s new drug, Paxlovid is just this plus ritonavir): WikipediaAnd here’s Ivermectin: WikipediaAs you can see they’re totally different structures. So, yes, it’s unsurprising they perform differently in the clinic. Completely different drugs often do. Ivermectin has been proven to be a protease inhibitor in a lab or so i've read. So it's the same mechanism of action. Post where you read it. I suspect he found it in the same place Reuters found it and posted this fact check of it: https://www.google.com/amp/s/mobile.reuters.com/article/amp/idUSL1N2R11T5Conclusion: they definitely don't work the same way. Although it's possible (although there is no evidence so far whatsoever that it even works at all) that Ivermectin combats Covid in a similar way, Ivermectin has multiple effects, some of which are potentially dangerous for humans, so even in the best case that Ivermectin does actually work to combat Covid (once again, no evidence so far), it may have worse side effects. The medicine Pfizer developed may also have side effects, but it is designed to specifically target a protease used in critical processes by the SARS-CoV-2 virus, and that hopefully limits unwanted and dangerous side effects. I remember reading it in a different fact check article and it admitted some in vitro study showed it. I just don't remember the article exactly and i never looked for the study. If you are talking about neurological side effects from ivermectin then you should know that ivermectin doesn't cross the blood brain barrier. Also i love how your fact check article uses Pfizer spokeperson as a source, very thrustworthy!
As opposed to the Ivermectin is a miracle drug crowd who are both competent and completely trustworthy? I don’t understand why people are so wedded to it. Let’s even assume it has some effectiveness in this domain.
Why would it be more effective incidentally, being designed for a completely different clinical scenario than specific Covid treatments being developed?
Unless I’ve missed it I haven’t even seen the manufacturers themselves extol its virtues as a Covid treatment, although I believe it’s licensed for generic reproduction, that’s still a big prestige boost.
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On November 06 2021 04:45 teeel141 wrote:Show nested quote +On November 06 2021 03:35 Acrofales wrote:On November 05 2021 23:51 JimmiC wrote:On November 05 2021 23:34 teeel141 wrote:On November 05 2021 23:24 JimmiC wrote:On November 05 2021 23:07 Sermokala wrote:
Its incredible what the difference between medicine that is tested for something and is proven good and medicine that is tested for something and not proven good in the eyes of scientists and the media. The stupid crowd being so obsessed with made up conspiracies. Ivermectin just does not work on covid, it has been tested it sucks. Sorry you were tricked by the same people that think JFK ghost is coming back to fight the deep state but you were. Like why is Merck (who makes ivermectin) not big evil big pharma? What makes them good big pharma? They have 48 billion in revenue. Pfizer he 42 Billion in revenue and like half the stock value. Their is not even a hint of logic to this stupidity. And Merck have an approved covid treatment its called Molnupiravir, and it is getting authorized and used before Pfizers was. Its just Ivermectin was not because that is not what it does. https://www.ctvnews.ca/health/coronavirus/u-k-authorizes-merck-antiviral-pill-1st-shown-to-treat-covid-19-1.5651764This crowd is basically mad that Antivan is not being prescribed for erectile disfunction without realizing that Viagra is and unlike Anitvan it actually helps with ED. Ivermectin is a generic drug and anybody can make it. There's no profit in it. I can't believe people still bring up Merck as some argument. Because Merck developed it and is still a major manufacturer of it? The same wait there is Generic Viagra and Pfizer is a major manufacturer of it...... And it is just stupidity at this point that it is talked about around covid, it does not work. On Oct. 11 drug company Merck applied for emergency use authorization from the FDA for its COVID-19 pill called 'Molnupiravir;' it is not the same as Ivermectin. They’re chemically different, meaning the structure of the molecules is not the same. According to the National Center for Biotechnology Information, a department within the National Institutes of Health's National Library of Medicine, the two have very different chemical structures. Ivermectin's formula is C48H74O14, while Molnupiravir's is C13H19N3O7
The organism they attack is different. Ivermectin attacks parasites. While the new Merck drug attacks RNA viruses.
They attack each organism differently. Ivermectin ruptures the cell membrane, which paralyzes and kills the parasite. While Molnupiravir corrupts the mRNA inside the cell, preventing the virus from replicating effectively.. The drugs are used to treat two completely different conditions. Ivermectin treats conditions caused by certain parasites. It's approved orally to treat intestinal strongyloidiasis and onchocerciasis (also known as river blindness) and topically to treat head lice and rosacea. Molnupiravir, on the other hand, is being studied to treat COVID-19. Right now, there is no evidence that Ivermectin treats COVID-19.
https://www.wusa9.com/article/news/verify/no-mercks-covid19-pill-molnupiravir-is-not-the-same-as-ivermectin-fact-check/65-60411c26-f515-4cbc-a955-fafd42d78780I vermectin has been pushed by right-wing politicians and activists promoting it as a supposed COVID treatment.[83][84][85] Misinformation about ivermectin's efficacy spread widely on social media, fueled by publications that have since been retracted,[86][87] misleading "meta-analysis" websites with substandard methods,[88][89] and conspiracy theories about efforts by governments and scientists to "suppress the evidence."[90][91]
In response to widespread misuse, the U.S. Food and Drug Administration, U.S. Centers for Disease Control, World Health Organization, American Medical Association, American Pharmacists Association, and American Society of Health-System Pharmacists issued statements in 2021 warning that ivermectin is not approved or authorized for the treatment or prevention of COVID-19, and advised against its use for that purpose outside of clinical trials.[60][22][92]
On September 1, 2021, health experts from the United States expressed concerns from reports of sharp increases in outpatient prescribing and dispensing of ivermectin with respect to levels before the pandemic.[93] These experts explain that the CDC has not authorized or approved ivermectin for the prevention or treatment of COVID-19. The American Association of Poison Control Centers has reported 1,440 cases of ivermectin poisoning through September 20, 2021, a three-fold increase compared to similar time periods in 2019 and 2020.[94] https://en.wikipedia.org/wiki/IvermectinOn November 05 2021 23:38 teeel141 wrote:On November 05 2021 23:05 ChristianS wrote:Not sure if you’re just trolling, but here’s PF-07321332 (Pfizer’s new drug, Paxlovid is just this plus ritonavir): WikipediaAnd here’s Ivermectin: WikipediaAs you can see they’re totally different structures. So, yes, it’s unsurprising they perform differently in the clinic. Completely different drugs often do. Ivermectin has been proven to be a protease inhibitor in a lab or so i've read. So it's the same mechanism of action. Post where you read it. I suspect he found it in the same place Reuters found it and posted this fact check of it: https://www.google.com/amp/s/mobile.reuters.com/article/amp/idUSL1N2R11T5Conclusion: they definitely don't work the same way. Although it's possible (although there is no evidence so far whatsoever that it even works at all) that Ivermectin combats Covid in a similar way, Ivermectin has multiple effects, some of which are potentially dangerous for humans, so even in the best case that Ivermectin does actually work to combat Covid (once again, no evidence so far), it may have worse side effects. The medicine Pfizer developed may also have side effects, but it is designed to specifically target a protease used in critical processes by the SARS-CoV-2 virus, and that hopefully limits unwanted and dangerous side effects. I remember reading it in a different fact check article and it admitted some in vitro study showed it. I just don't remember the article exactly and i never looked for the study. If you are talking about neurological side effects from ivermectin then you should know that ivermectin doesn't cross the blood brain barrier. Also i love how your fact check article uses Pfizer spokeperson as a source, very thrustworthy!
Why would you think that a successful in vitro experiment would imply that we ought to take it? A test-tube experiment is not the same as having huge, randomized, controlled sample sizes of actual human beings.
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On November 06 2021 05:18 WombaT wrote:Show nested quote +On November 06 2021 04:45 teeel141 wrote:On November 06 2021 03:35 Acrofales wrote:On November 05 2021 23:51 JimmiC wrote:On November 05 2021 23:34 teeel141 wrote:On November 05 2021 23:24 JimmiC wrote:On November 05 2021 23:07 Sermokala wrote:
Its incredible what the difference between medicine that is tested for something and is proven good and medicine that is tested for something and not proven good in the eyes of scientists and the media. The stupid crowd being so obsessed with made up conspiracies. Ivermectin just does not work on covid, it has been tested it sucks. Sorry you were tricked by the same people that think JFK ghost is coming back to fight the deep state but you were. Like why is Merck (who makes ivermectin) not big evil big pharma? What makes them good big pharma? They have 48 billion in revenue. Pfizer he 42 Billion in revenue and like half the stock value. Their is not even a hint of logic to this stupidity. And Merck have an approved covid treatment its called Molnupiravir, and it is getting authorized and used before Pfizers was. Its just Ivermectin was not because that is not what it does. https://www.ctvnews.ca/health/coronavirus/u-k-authorizes-merck-antiviral-pill-1st-shown-to-treat-covid-19-1.5651764This crowd is basically mad that Antivan is not being prescribed for erectile disfunction without realizing that Viagra is and unlike Anitvan it actually helps with ED. Ivermectin is a generic drug and anybody can make it. There's no profit in it. I can't believe people still bring up Merck as some argument. Because Merck developed it and is still a major manufacturer of it? The same wait there is Generic Viagra and Pfizer is a major manufacturer of it...... And it is just stupidity at this point that it is talked about around covid, it does not work. On Oct. 11 drug company Merck applied for emergency use authorization from the FDA for its COVID-19 pill called 'Molnupiravir;' it is not the same as Ivermectin. They’re chemically different, meaning the structure of the molecules is not the same. According to the National Center for Biotechnology Information, a department within the National Institutes of Health's National Library of Medicine, the two have very different chemical structures. Ivermectin's formula is C48H74O14, while Molnupiravir's is C13H19N3O7
The organism they attack is different. Ivermectin attacks parasites. While the new Merck drug attacks RNA viruses.
They attack each organism differently. Ivermectin ruptures the cell membrane, which paralyzes and kills the parasite. While Molnupiravir corrupts the mRNA inside the cell, preventing the virus from replicating effectively.. The drugs are used to treat two completely different conditions. Ivermectin treats conditions caused by certain parasites. It's approved orally to treat intestinal strongyloidiasis and onchocerciasis (also known as river blindness) and topically to treat head lice and rosacea. Molnupiravir, on the other hand, is being studied to treat COVID-19. Right now, there is no evidence that Ivermectin treats COVID-19.
https://www.wusa9.com/article/news/verify/no-mercks-covid19-pill-molnupiravir-is-not-the-same-as-ivermectin-fact-check/65-60411c26-f515-4cbc-a955-fafd42d78780I vermectin has been pushed by right-wing politicians and activists promoting it as a supposed COVID treatment.[83][84][85] Misinformation about ivermectin's efficacy spread widely on social media, fueled by publications that have since been retracted,[86][87] misleading "meta-analysis" websites with substandard methods,[88][89] and conspiracy theories about efforts by governments and scientists to "suppress the evidence."[90][91]
In response to widespread misuse, the U.S. Food and Drug Administration, U.S. Centers for Disease Control, World Health Organization, American Medical Association, American Pharmacists Association, and American Society of Health-System Pharmacists issued statements in 2021 warning that ivermectin is not approved or authorized for the treatment or prevention of COVID-19, and advised against its use for that purpose outside of clinical trials.[60][22][92]
On September 1, 2021, health experts from the United States expressed concerns from reports of sharp increases in outpatient prescribing and dispensing of ivermectin with respect to levels before the pandemic.[93] These experts explain that the CDC has not authorized or approved ivermectin for the prevention or treatment of COVID-19. The American Association of Poison Control Centers has reported 1,440 cases of ivermectin poisoning through September 20, 2021, a three-fold increase compared to similar time periods in 2019 and 2020.[94] https://en.wikipedia.org/wiki/IvermectinOn November 05 2021 23:38 teeel141 wrote:On November 05 2021 23:05 ChristianS wrote:Not sure if you’re just trolling, but here’s PF-07321332 (Pfizer’s new drug, Paxlovid is just this plus ritonavir): WikipediaAnd here’s Ivermectin: WikipediaAs you can see they’re totally different structures. So, yes, it’s unsurprising they perform differently in the clinic. Completely different drugs often do. Ivermectin has been proven to be a protease inhibitor in a lab or so i've read. So it's the same mechanism of action. Post where you read it. I suspect he found it in the same place Reuters found it and posted this fact check of it: https://www.google.com/amp/s/mobile.reuters.com/article/amp/idUSL1N2R11T5Conclusion: they definitely don't work the same way. Although it's possible (although there is no evidence so far whatsoever that it even works at all) that Ivermectin combats Covid in a similar way, Ivermectin has multiple effects, some of which are potentially dangerous for humans, so even in the best case that Ivermectin does actually work to combat Covid (once again, no evidence so far), it may have worse side effects. The medicine Pfizer developed may also have side effects, but it is designed to specifically target a protease used in critical processes by the SARS-CoV-2 virus, and that hopefully limits unwanted and dangerous side effects. I remember reading it in a different fact check article and it admitted some in vitro study showed it. I just don't remember the article exactly and i never looked for the study. If you are talking about neurological side effects from ivermectin then you should know that ivermectin doesn't cross the blood brain barrier. Also i love how your fact check article uses Pfizer spokeperson as a source, very thrustworthy! As opposed to the Ivermectin is a miracle drug crowd who are both competent and completely trustworthy? I don’t understand why people are so wedded to it. Let’s even assume it has some effectiveness in this domain. Why would it be more effective incidentally, being designed for a completely different clinical scenario than specific Covid treatments being developed? Unless I’ve missed it I haven’t even seen the manufacturers themselves extol its virtues as a Covid treatment, although I believe it’s licensed for generic reproduction, that’s still a big prestige boost.
Merck the company that makes ivermectin has a drug in development that costs 19-25$ to produce for a regimen and they plan to charge 700$. How is that compared to a prestige boost?
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On November 06 2021 05:43 DarkPlasmaBall wrote:Show nested quote +On November 06 2021 04:45 teeel141 wrote:On November 06 2021 03:35 Acrofales wrote:On November 05 2021 23:51 JimmiC wrote:On November 05 2021 23:34 teeel141 wrote:On November 05 2021 23:24 JimmiC wrote:On November 05 2021 23:07 Sermokala wrote:
Its incredible what the difference between medicine that is tested for something and is proven good and medicine that is tested for something and not proven good in the eyes of scientists and the media. The stupid crowd being so obsessed with made up conspiracies. Ivermectin just does not work on covid, it has been tested it sucks. Sorry you were tricked by the same people that think JFK ghost is coming back to fight the deep state but you were. Like why is Merck (who makes ivermectin) not big evil big pharma? What makes them good big pharma? They have 48 billion in revenue. Pfizer he 42 Billion in revenue and like half the stock value. Their is not even a hint of logic to this stupidity. And Merck have an approved covid treatment its called Molnupiravir, and it is getting authorized and used before Pfizers was. Its just Ivermectin was not because that is not what it does. https://www.ctvnews.ca/health/coronavirus/u-k-authorizes-merck-antiviral-pill-1st-shown-to-treat-covid-19-1.5651764This crowd is basically mad that Antivan is not being prescribed for erectile disfunction without realizing that Viagra is and unlike Anitvan it actually helps with ED. Ivermectin is a generic drug and anybody can make it. There's no profit in it. I can't believe people still bring up Merck as some argument. Because Merck developed it and is still a major manufacturer of it? The same wait there is Generic Viagra and Pfizer is a major manufacturer of it...... And it is just stupidity at this point that it is talked about around covid, it does not work. On Oct. 11 drug company Merck applied for emergency use authorization from the FDA for its COVID-19 pill called 'Molnupiravir;' it is not the same as Ivermectin. They’re chemically different, meaning the structure of the molecules is not the same. According to the National Center for Biotechnology Information, a department within the National Institutes of Health's National Library of Medicine, the two have very different chemical structures. Ivermectin's formula is C48H74O14, while Molnupiravir's is C13H19N3O7
The organism they attack is different. Ivermectin attacks parasites. While the new Merck drug attacks RNA viruses.
They attack each organism differently. Ivermectin ruptures the cell membrane, which paralyzes and kills the parasite. While Molnupiravir corrupts the mRNA inside the cell, preventing the virus from replicating effectively.. The drugs are used to treat two completely different conditions. Ivermectin treats conditions caused by certain parasites. It's approved orally to treat intestinal strongyloidiasis and onchocerciasis (also known as river blindness) and topically to treat head lice and rosacea. Molnupiravir, on the other hand, is being studied to treat COVID-19. Right now, there is no evidence that Ivermectin treats COVID-19.
https://www.wusa9.com/article/news/verify/no-mercks-covid19-pill-molnupiravir-is-not-the-same-as-ivermectin-fact-check/65-60411c26-f515-4cbc-a955-fafd42d78780I vermectin has been pushed by right-wing politicians and activists promoting it as a supposed COVID treatment.[83][84][85] Misinformation about ivermectin's efficacy spread widely on social media, fueled by publications that have since been retracted,[86][87] misleading "meta-analysis" websites with substandard methods,[88][89] and conspiracy theories about efforts by governments and scientists to "suppress the evidence."[90][91]
In response to widespread misuse, the U.S. Food and Drug Administration, U.S. Centers for Disease Control, World Health Organization, American Medical Association, American Pharmacists Association, and American Society of Health-System Pharmacists issued statements in 2021 warning that ivermectin is not approved or authorized for the treatment or prevention of COVID-19, and advised against its use for that purpose outside of clinical trials.[60][22][92]
On September 1, 2021, health experts from the United States expressed concerns from reports of sharp increases in outpatient prescribing and dispensing of ivermectin with respect to levels before the pandemic.[93] These experts explain that the CDC has not authorized or approved ivermectin for the prevention or treatment of COVID-19. The American Association of Poison Control Centers has reported 1,440 cases of ivermectin poisoning through September 20, 2021, a three-fold increase compared to similar time periods in 2019 and 2020.[94] https://en.wikipedia.org/wiki/IvermectinOn November 05 2021 23:38 teeel141 wrote:On November 05 2021 23:05 ChristianS wrote:Not sure if you’re just trolling, but here’s PF-07321332 (Pfizer’s new drug, Paxlovid is just this plus ritonavir): WikipediaAnd here’s Ivermectin: WikipediaAs you can see they’re totally different structures. So, yes, it’s unsurprising they perform differently in the clinic. Completely different drugs often do. Ivermectin has been proven to be a protease inhibitor in a lab or so i've read. So it's the same mechanism of action. Post where you read it. I suspect he found it in the same place Reuters found it and posted this fact check of it: https://www.google.com/amp/s/mobile.reuters.com/article/amp/idUSL1N2R11T5Conclusion: they definitely don't work the same way. Although it's possible (although there is no evidence so far whatsoever that it even works at all) that Ivermectin combats Covid in a similar way, Ivermectin has multiple effects, some of which are potentially dangerous for humans, so even in the best case that Ivermectin does actually work to combat Covid (once again, no evidence so far), it may have worse side effects. The medicine Pfizer developed may also have side effects, but it is designed to specifically target a protease used in critical processes by the SARS-CoV-2 virus, and that hopefully limits unwanted and dangerous side effects. I remember reading it in a different fact check article and it admitted some in vitro study showed it. I just don't remember the article exactly and i never looked for the study. If you are talking about neurological side effects from ivermectin then you should know that ivermectin doesn't cross the blood brain barrier. Also i love how your fact check article uses Pfizer spokeperson as a source, very thrustworthy! Why would you think that a successful in vitro experiment would imply that we ought to take it? A test-tube experiment is not the same as having huge, randomized, controlled sample sizes of actual human beings.
I wish there was some good prestigious study that would settle this question once and for all. I know of the together trial that had ivermectin in it, but they used a small dose and late in the disease. How would it help once the virus is no longer replicating and youre just dealing with inflammation? Yet it's used as proof.
I actually think the whole pharmaceutical industry is rotten to the core and completely evil. And if ivermectin was good for covid they would 100% atleast try to kill the drug.
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Also speaking of fact checkers, it's super interesting how they never fact checked herd immunity claims for example. The virus went from 2.5 r0 with wuhan strain to 6-8 r0 with delta. And waning immunity started to become a problem at the same time. Meanwhile the herd immunity claim went from 60-70% to 80% later to 90%. How come they didn't point out that you would need above 100%?
Fact checking is just there to criticize any claims that go against the narrative (valid or not).
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On November 06 2021 06:17 teeel141 wrote:
Also speaking of fact checkers, it's super interesting how they never fact checked herd immunity claims for example. The virus went from 2.5 r0 with wuhan strain to 6-8 r0 with delta. And waning immunity started to become a problem at the same time. Meanwhile the herd immunity claim went from 60-70% to 80% later to 90%. How come they didn't point out that you would need above 100%?
Fact checking is just there to criticize any claims that go against the narrative (valid or not). What? Your answering your own question. Why did herd immunity % go up? Because a more infectious strain emerged (delta).
Are you blaming fact checkers for not knowing the future?
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On November 05 2021 23:38 teeel141 wrote:Show nested quote +On November 05 2021 23:05 ChristianS wrote:Not sure if you’re just trolling, but here’s PF-07321332 (Pfizer’s new drug, Paxlovid is just this plus ritonavir): WikipediaAnd here’s Ivermectin: WikipediaAs you can see they’re totally different structures. So, yes, it’s unsurprising they perform differently in the clinic. Completely different drugs often do. Ivermectin has been proven to be a protease inhibitor in a lab or so i've read. So it's the same mechanism of action.
“Protease inhibitor” is an extremely vague classification. Protease just means a protein that cuts up other proteins, and “protease inhibitor” just means there’s some protease it would at least partially slow down. A blood thinner might be a protease inhibitor but it wouldn’t help me much against a viral infection.
You should understand that drug development is extremely complicated and it’s not remotely uncommon for two drugs that appear to be inhibitors for the same protein at the same binding site to have wildly different functionality. In this case they don’t even apparently have the same mechanism; Wikipedia seems to indicate Ivermectin acts primarily on neuronal glutamate-gated chloride channels.
TL;DR: different drugs do different stuff, this shouldn’t surprise anyone.
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On November 06 2021 07:02 Gorsameth wrote:Show nested quote +On November 06 2021 06:17 teeel141 wrote:
Also speaking of fact checkers, it's super interesting how they never fact checked herd immunity claims for example. The virus went from 2.5 r0 with wuhan strain to 6-8 r0 with delta. And waning immunity started to become a problem at the same time. Meanwhile the herd immunity claim went from 60-70% to 80% later to 90%. How come they didn't point out that you would need above 100%?
Fact checking is just there to criticize any claims that go against the narrative (valid or not). What? Your answering your own question. Why did herd immunity % go up? Because a more infectious strain emerged (delta). Are you blaming fact checkers for not knowing the future?
This is another level of stupid. Not seen in this thread before. :<
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Northern Ireland27265 Posts
On November 06 2021 05:52 teeel141 wrote:Show nested quote +On November 06 2021 05:18 WombaT wrote:On November 06 2021 04:45 teeel141 wrote:On November 06 2021 03:35 Acrofales wrote:On November 05 2021 23:51 JimmiC wrote:On November 05 2021 23:34 teeel141 wrote:On November 05 2021 23:24 JimmiC wrote:On November 05 2021 23:07 Sermokala wrote:
Its incredible what the difference between medicine that is tested for something and is proven good and medicine that is tested for something and not proven good in the eyes of scientists and the media. The stupid crowd being so obsessed with made up conspiracies. Ivermectin just does not work on covid, it has been tested it sucks. Sorry you were tricked by the same people that think JFK ghost is coming back to fight the deep state but you were. Like why is Merck (who makes ivermectin) not big evil big pharma? What makes them good big pharma? They have 48 billion in revenue. Pfizer he 42 Billion in revenue and like half the stock value. Their is not even a hint of logic to this stupidity. And Merck have an approved covid treatment its called Molnupiravir, and it is getting authorized and used before Pfizers was. Its just Ivermectin was not because that is not what it does. https://www.ctvnews.ca/health/coronavirus/u-k-authorizes-merck-antiviral-pill-1st-shown-to-treat-covid-19-1.5651764This crowd is basically mad that Antivan is not being prescribed for erectile disfunction without realizing that Viagra is and unlike Anitvan it actually helps with ED. Ivermectin is a generic drug and anybody can make it. There's no profit in it. I can't believe people still bring up Merck as some argument. Because Merck developed it and is still a major manufacturer of it? The same wait there is Generic Viagra and Pfizer is a major manufacturer of it...... And it is just stupidity at this point that it is talked about around covid, it does not work. On Oct. 11 drug company Merck applied for emergency use authorization from the FDA for its COVID-19 pill called 'Molnupiravir;' it is not the same as Ivermectin. They’re chemically different, meaning the structure of the molecules is not the same. According to the National Center for Biotechnology Information, a department within the National Institutes of Health's National Library of Medicine, the two have very different chemical structures. Ivermectin's formula is C48H74O14, while Molnupiravir's is C13H19N3O7
The organism they attack is different. Ivermectin attacks parasites. While the new Merck drug attacks RNA viruses.
They attack each organism differently. Ivermectin ruptures the cell membrane, which paralyzes and kills the parasite. While Molnupiravir corrupts the mRNA inside the cell, preventing the virus from replicating effectively.. The drugs are used to treat two completely different conditions. Ivermectin treats conditions caused by certain parasites. It's approved orally to treat intestinal strongyloidiasis and onchocerciasis (also known as river blindness) and topically to treat head lice and rosacea. Molnupiravir, on the other hand, is being studied to treat COVID-19. Right now, there is no evidence that Ivermectin treats COVID-19.
https://www.wusa9.com/article/news/verify/no-mercks-covid19-pill-molnupiravir-is-not-the-same-as-ivermectin-fact-check/65-60411c26-f515-4cbc-a955-fafd42d78780I vermectin has been pushed by right-wing politicians and activists promoting it as a supposed COVID treatment.[83][84][85] Misinformation about ivermectin's efficacy spread widely on social media, fueled by publications that have since been retracted,[86][87] misleading "meta-analysis" websites with substandard methods,[88][89] and conspiracy theories about efforts by governments and scientists to "suppress the evidence."[90][91]
In response to widespread misuse, the U.S. Food and Drug Administration, U.S. Centers for Disease Control, World Health Organization, American Medical Association, American Pharmacists Association, and American Society of Health-System Pharmacists issued statements in 2021 warning that ivermectin is not approved or authorized for the treatment or prevention of COVID-19, and advised against its use for that purpose outside of clinical trials.[60][22][92]
On September 1, 2021, health experts from the United States expressed concerns from reports of sharp increases in outpatient prescribing and dispensing of ivermectin with respect to levels before the pandemic.[93] These experts explain that the CDC has not authorized or approved ivermectin for the prevention or treatment of COVID-19. The American Association of Poison Control Centers has reported 1,440 cases of ivermectin poisoning through September 20, 2021, a three-fold increase compared to similar time periods in 2019 and 2020.[94] https://en.wikipedia.org/wiki/IvermectinOn November 05 2021 23:38 teeel141 wrote:On November 05 2021 23:05 ChristianS wrote:Not sure if you’re just trolling, but here’s PF-07321332 (Pfizer’s new drug, Paxlovid is just this plus ritonavir): WikipediaAnd here’s Ivermectin: WikipediaAs you can see they’re totally different structures. So, yes, it’s unsurprising they perform differently in the clinic. Completely different drugs often do. Ivermectin has been proven to be a protease inhibitor in a lab or so i've read. So it's the same mechanism of action. Post where you read it. I suspect he found it in the same place Reuters found it and posted this fact check of it: https://www.google.com/amp/s/mobile.reuters.com/article/amp/idUSL1N2R11T5Conclusion: they definitely don't work the same way. Although it's possible (although there is no evidence so far whatsoever that it even works at all) that Ivermectin combats Covid in a similar way, Ivermectin has multiple effects, some of which are potentially dangerous for humans, so even in the best case that Ivermectin does actually work to combat Covid (once again, no evidence so far), it may have worse side effects. The medicine Pfizer developed may also have side effects, but it is designed to specifically target a protease used in critical processes by the SARS-CoV-2 virus, and that hopefully limits unwanted and dangerous side effects. I remember reading it in a different fact check article and it admitted some in vitro study showed it. I just don't remember the article exactly and i never looked for the study. If you are talking about neurological side effects from ivermectin then you should know that ivermectin doesn't cross the blood brain barrier. Also i love how your fact check article uses Pfizer spokeperson as a source, very thrustworthy! As opposed to the Ivermectin is a miracle drug crowd who are both competent and completely trustworthy? I don’t understand why people are so wedded to it. Let’s even assume it has some effectiveness in this domain. Why would it be more effective incidentally, being designed for a completely different clinical scenario than specific Covid treatments being developed? Unless I’ve missed it I haven’t even seen the manufacturers themselves extol its virtues as a Covid treatment, although I believe it’s licensed for generic reproduction, that’s still a big prestige boost. Merck the company that makes ivermectin has a drug in development that costs 19-25$ to produce for a regimen and they plan to charge 700$. How is that compared to a prestige boost?
So another drug that isn’t Invermectin then?
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EPT
