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Although this thread does not function under the same strict guidelines as the USPMT, it is still a general practice on TL to provide a source with an explanation on why it is relevant and what purpose it adds to the discussion. Failure to do so will result in a mod action.
Sbrubbles
Profile Joined October 2010
Brazil5776 Posts
April 11 2018 13:20 GMT
#21521
On April 11 2018 21:06 farvacola wrote:
Well my experience has been the opposite, namely that tylenol is one of those meds that a lot of people take when sick without ever engaging with whether it's actually helping. To make deciphering its practical effects even harder, its cold/flu applications tend to mix it with other compounds like guaifenesin, dextromethorphan, or pseudoephedrine.


Fair enough.

On April 11 2018 21:07 Gorsameth wrote:
Google gives me a study from 2015, but explains both stances.

That study tested for the amount of virus in the body between those taking paracetamol and a control group and found no significant difference.
Which makes sense since Paracetamol isn't supposed to combat the virus, just its symptoms.

So yes taking it when you have the cold has a positive effect because the symptoms are being suppressed.
It however does nothing to limit the duration of your illness.

https://www.nhs.uk/news/heart-and-lungs/is-paracetamol-any-good-for-treating-flu/


Thanks. That's a nice overview of the study, very detailed, yet concise.

Bora Pain minha porra!
Ghostcom
Profile Joined March 2010
Denmark4782 Posts
April 11 2018 13:28 GMT
#21522
But it should be stressed this is something paracetamol is not designed to do. Paracetamol is designed to relieve symptoms, not cure any underlying infection.


I think whoever wrote that didn't actually bother with reading the introduction to the trial. Otherwise it's a fine summary.
Acrofales
Profile Joined August 2010
Spain18123 Posts
Last Edited: 2018-04-11 13:35:34
April 11 2018 13:32 GMT
#21523
On April 11 2018 21:23 Dan HH wrote:
Show nested quote +
On April 11 2018 20:57 Sbrubbles wrote:
On April 11 2018 20:54 farvacola wrote:
What makes what Ghostcom posted "counterintuitive?" It seems the opposite to me.


After using paracetamol my whole life and personally seing it have positive effects on myself and seeing it do the same on others, yes, I would consider it just being a placebo effect counterintuitive.

Though lots of things in life work because people believe they will work, most things work because there's an active mechanism behind it working, therefore I would consider any claim about medicine that "works" purely because of placebo effect counterintuitive. Does my intuition go against yours? Also, by counterintuitive I'm not saying it can't be right, I know placebos can work.

I normally don't take anything when I have a cold, those positive effects come simply from the passage of time

Show nested quote +
On April 11 2018 21:13 Acrofales wrote:
In any case, it is quite an effective painkiller, and helps with some of the symptoms, such as headaches or muscle pains, that can be symptoms of flu, and will, in that way, simply make you feel a bit less shitty while your body deals with the disease.

That's a good point, I guess there are so many strains out there and people react differently to them. For me the annoyance is limited to the nose and throat. Never had headaches/pain during a cold, I can see why paracetamol may be useful to people that do.

Influenza and common cold are two different things as well. Don't confuse them! Influenza (in all its variations) is a significantly more serious disease than the common cold.

E: here's what the CDC has to say about them, and a handy list of symptoms https://www.cdc.gov/flu/about/qa/coldflu.htm
LegalLord
Profile Blog Joined April 2013
United States13779 Posts
April 11 2018 15:11 GMT
#21524
I take something to feel less shitty, and IME cough syrup is the only thing that has any effect. Dunno if it has any effect in terms of combating the disease but for something that isn't a particular life risk for most healthy people it's certainly important to feel less bad.
History will sooner or later sweep the European Union away without mercy.
sc-darkness
Profile Joined August 2017
856 Posts
April 11 2018 16:32 GMT
#21525
I think garlic is the best common cold medicine. You eat it every day and very few people would want to be around you which significantly reduces your risk of getting infected. :D
RolleMcKnolle
Profile Blog Joined May 2010
Germany1054 Posts
April 11 2018 17:43 GMT
#21526
There are quite a few studies suggesting zinc could shorten the duration of a common cold:
https://www.ncbi.nlm.nih.gov/pubmed/28480298

So there are some kinds of "medication".
On the topic of taking paracetamol during colds, I suppose if you feel a lessening of symptoms you could just take it. As long as you aren't sick too often or for prolonged amounts of time the risks stemming from paracetamol are almost negligible. So if there is some way it helps you even if its just the placebo effect, why not.
IgnE
Profile Joined November 2010
United States7681 Posts
April 11 2018 19:16 GMT
#21527
does zinc shorten the duration of the common cold or does a zinc deficiency lengthen the duration?

The unrealistic sound of these propositions is indicative, not of their utopian character, but of the strength of the forces which prevent their realization.
RolleMcKnolle
Profile Blog Joined May 2010
Germany1054 Posts
April 11 2018 20:32 GMT
#21528
considering zinc deficiency is quite the rare occurence: the first option applies.
IgnE
Profile Joined November 2010
United States7681 Posts
April 11 2018 20:43 GMT
#21529
how do you know zinc deficiency is rare? maybe we should be defining it as a state w a compromised immune system which takes longer to fight off colds
The unrealistic sound of these propositions is indicative, not of their utopian character, but of the strength of the forces which prevent their realization.
m4ini
Profile Joined February 2014
4215 Posts
Last Edited: 2018-04-12 00:55:15
April 12 2018 00:54 GMT
#21530
On April 11 2018 22:17 Ghostcom wrote:
Show nested quote +
On April 11 2018 21:07 Gorsameth wrote:
Google gives me a study from 2015, but explains both stances.

That study tested for the amount of virus in the body between those taking paracetamol and a control group and found no significant difference.
Which makes sense since Paracetamol isn't supposed to combat the virus, just its symptoms.

So yes taking it when you have the cold has a positive effect because the symptoms are being suppressed.
It however does nothing to limit the duration of your illness.

https://www.nhs.uk/news/heart-and-lungs/is-paracetamol-any-good-for-treating-flu/


The study by Jeffries et al (link) also had a questionnaire measuring symptoms. Paracetamol didn't influence these either. And the theory of the study in question was actually that paracetamol would INCREASE the viral load due to it's anti-pyretic effects. The study has a number of flaws, but it is also the only study carried out so far. I think the overall conclusions are quite reasonable.

I wouldn't recommend taking NSAIDs regularly for a cold/influenza.

EDIT: This is a very odd topic for a politics thread though.


Paracetamol isn't a NSAID though. Since my wife is asthmatic, i wanted to point that out (edit: asthmatics can't take NSAIDs, since they can induce attacks). Not sure if you were implying that, but since you were talking paracetamol, you might've mistaken that with Ibuprofen.
On track to MA1950A.
Ghostcom
Profile Joined March 2010
Denmark4782 Posts
Last Edited: 2018-04-12 07:27:00
April 12 2018 06:20 GMT
#21531
On April 12 2018 09:54 m4ini wrote:
Show nested quote +
On April 11 2018 22:17 Ghostcom wrote:
On April 11 2018 21:07 Gorsameth wrote:
Google gives me a study from 2015, but explains both stances.

That study tested for the amount of virus in the body between those taking paracetamol and a control group and found no significant difference.
Which makes sense since Paracetamol isn't supposed to combat the virus, just its symptoms.

So yes taking it when you have the cold has a positive effect because the symptoms are being suppressed.
It however does nothing to limit the duration of your illness.

https://www.nhs.uk/news/heart-and-lungs/is-paracetamol-any-good-for-treating-flu/


The study by Jeffries et al (link) also had a questionnaire measuring symptoms. Paracetamol didn't influence these either. And the theory of the study in question was actually that paracetamol would INCREASE the viral load due to it's anti-pyretic effects. The study has a number of flaws, but it is also the only study carried out so far. I think the overall conclusions are quite reasonable.

I wouldn't recommend taking NSAIDs regularly for a cold/influenza.

EDIT: This is a very odd topic for a politics thread though.


Paracetamol isn't a NSAID though. Since my wife is asthmatic, i wanted to point that out (edit: asthmatics can't take NSAIDs, since they can induce attacks). Not sure if you were implying that, but since you were talking paracetamol, you might've mistaken that with Ibuprofen.


I'm an MD, I'm fully aware. The post above by acrofales suggested using nsaids as anti-pyretics in place of paracetamol, which certainly can't be recommended.

And asthmatics can most certainly take NSAIDs. Only about 10-20% (depending on study) are sensitive to them and risk an attack (I have for example yet to experience an attack and I've ingested quite a lot of ibuprofen during my elite sports career in my youth.)
m4ini
Profile Joined February 2014
4215 Posts
Last Edited: 2018-04-12 12:17:22
April 12 2018 12:16 GMT
#21532
Missed that one, my bad then.

That said, 1 in 10/1 in 5 being in risk of a potentially deadly asthma attack isn't really "only". I have taken Ibu before in my youth, trying to (obviously with no success, but if you're desperate.. i'm asthmatic too, entirely unmedicated) combat my cluster headaches - my wife, 10 years ago, almost died because of an induced attack. Without exaggeration, it was very close.

At least our GP is not just hesitant, but flatout refuses to prescribe NSAIDs to me/her. Even though i personally haven't had a problem with them. Maybe i should've said "shouldn't take" instead of "can't take".
On track to MA1950A.
Ghostcom
Profile Joined March 2010
Denmark4782 Posts
April 12 2018 20:15 GMT
#21533
Its a specific subgroup of asthmatics who can’t tolerate nsaids. Just like not all asthmatics have exercise induced attacks.
sc-darkness
Profile Joined August 2017
856 Posts
April 12 2018 21:45 GMT
#21534
On April 12 2018 21:16 m4ini wrote:
Missed that one, my bad then.

That said, 1 in 10/1 in 5 being in risk of a potentially deadly asthma attack isn't really "only". I have taken Ibu before in my youth, trying to (obviously with no success, but if you're desperate.. i'm asthmatic too, entirely unmedicated) combat my cluster headaches - my wife, 10 years ago, almost died because of an induced attack. Without exaggeration, it was very close.

At least our GP is not just hesitant, but flatout refuses to prescribe NSAIDs to me/her. Even though i personally haven't had a problem with them. Maybe i should've said "shouldn't take" instead of "can't take".


Wikipedia isn't the best source, but it says paracetomol isn't NSAID, so it's fine then? I guess you have an option if it's safe, but I don't know if that's correct. Better ask your doctor if unsure.


Paracetamol (acetaminophen) is generally not considered an NSAID because it has only little anti-inflammatory activity. It treats pain mainly by blocking COX-2 mostly in the central nervous system, but not much in the rest of the body.[8][9]
Nyxisto
Profile Joined August 2010
Germany6287 Posts
April 13 2018 04:19 GMT
#21535
Interesting take on the Portuguese left


ANTONIO COSTA, Portugal’s affable prime minister, greets your columnist with a broad grin as he settles his hefty frame into a sofa in his official residence. He has a lot to smile about. Lisbon, among Europe’s hottest tourist destinations, is enjoying a mini startup boom. Portugal’s footballers are the European champions, and its politicians have nabbed a clutch of senior international jobs. And above all, he is the winner of a high-stakes political gamble.

When Mr Costa’s Socialist Party lost an election in 2015 to the centre-right (and confusingly named) Social Democrats, who had overseen a harsh EU-imposed austerity programme during a three-year €78bn ($107bn) bail-out, most observers expected the Socialists to prop them up in a left-right “grand coalition” of the sort now common across Europe. Instead Mr Costa, the son of a communist intellectual from Goa, Portugal’s old colony in India, convinced two hard-left parties—the old-school Communists and the modish Left Bloc—to support a minority Socialist government in exchange for modest policy concessions.

Nothing like this had been tried before in Portugal. Mr Costa’s new friends wanted, variously, to write off debt, leave the euro zone, renationalise vast swathes of industry and quit NATO. The fury was swift, deep and near-universal. Foes nicknamed Mr Costa’s experiment the geringonça (“contraption”), and gave it six months at most. Portugal’s president threatened to reject the proposed government outright. Creditors feared a free-spending leftist government would send investors packing.

Yet over two years later the contraption is grinding along and the sky has failed to fall in. Some wage and pension cuts have been reversed, firms are creating jobs at a neat clip, foreign investors are eagerly sniffing around and the public finances are in rude health; the government hopes to balance the books next year. Portugal has become a bond-market darling while claiming to stand in the vanguard of the battle against austerity. “We showed that there is an alternative to ‘There is no alternative,’” says Mr Costa. He enjoys approval ratings most leaders would kill for. Little wonder Europe’s beleaguered social democrats are beating down his door.

Does Portugal have anything to teach them? Mr Costa notes modestly that “every country is specific.” Still, he has one or two ideas. Grand coalitions play into the hands of populists, he suggests, because they signal to voters that political contests are redundant. He cites Germany, the Netherlands and Austria as cautionary tales; social democratic parties in all three are floundering after governing with the right. An aide says that “civilised conflict” helps keep politics, and parties, alive. That is a bracing message in an era of cosy political pacts.

Pedro Magalhães, a political scientist at the University of Lisbon, points out that Portugal’s Socialists differ from many of their counterparts in Europe. The party sprang not from trade unions but from elites desperate to establish a bulwark against communism after the end of military rule in the mid-1970s. The party thus seeks power, not purity, and the election result gave a united left the chance to block a right-wing minority government. No one likes grand coalitions, but in many countries parliamentary arithmetic leaves centrist parties no choice but to team up against the extremes. Mr Costa’s gambit was bold, but also opportune.

The Left Bloc and the Communists hammer the Socialists on matters like foreign policy but hold fire when it matters, notably on the budget. Neither is fully comfortable with the deal, but both know they would find the centre-right alternative less palatable, and they can take credit for policies like raising the minimum wage or halting transport privatisations. Helpfully, the growth in Socialist support since 2015 has come largely at the expense of the right, soothing the leftists’ fear that the contraption would turn out to be their death warrant. Mr Costa says the arrangement will survive until next year’s election. And beyond? “Why not?”

Even Mr Costa’s opponents concede that he is a canny operator. But his success has been oiled by a healthy squirt of good luck. The Socialists assumed office as Portugal’s recovery took off, aided by growth in the European markets that take 70% of its exports, and built on the measures taken by the previous government. The European Central Bank’s bond-buying had calmed markets. Tourism has boomed, thanks to instability in other warm countries. Perhaps most importantly immigration, the issue tearing apart so many European parties of the left, does not animate Portuguese voters. It is the departure of people that causes a bigger headache: during the crisis 250,000 Portuguese, disproportionately of working age, upped sticks in four years.

Portugal’s squeeze on spending had to be financed from somewhere. The axe has fallen on public investment, which was slashed in 2016 to the lowest level in the EU. Mario Centeno, the finance minister, says this was largely the result of a temporary drop in EU subsidies, and chuckles at the sight of “so-called neoliberals” who now consider Keynes their “god”. He prefers to draw attention to Portugal’s healthier banks and buzzing universities, though he adds that investment is climbing again. Another fear surrounds Portugal’s huge debt, which explains Mr Centeno’s relentless focus on the deficit.

As this suggests, Portugal’s left-wing government is thriving partly because it is not especially left-wing. For now it is fixated on deficits and debt rather than investment and public services. A centre-right government would be doing much the same. And so, despite Mr Costa’s warm words, the contraption will surely prove to be a temporary marriage of convenience; his party is already said quietly to be putting out feelers to the Social Democrats. European leftists may find inspiration in Portugal. But they will have to seek ideas elsewhere.
warding
Profile Joined August 2005
Portugal2394 Posts
April 13 2018 11:02 GMT
#21536
That's spot on. António Costa is both an extremely lucky man and a very savvy politician. After Durão Barroso and Guterres, it's not difficult to see him taking a high-profile role in an international institution next.

I was super pissed when he maneuvered in 2015 to form an agreement with the extreme left loons after he finished 2nd in the election. What happened after that was genius: he basically kept the course that the previous center-right government had taken, reaping the benefits of the economic expansion while continuing to cut down the deficit (AKA AUSTERITY). The right is happy with public policy and the center-left is happy because it's in power and they somehow think 'austerity is over'.

Now the extreme left are pissed because António Costa isn't bringing down the labor reforms imposed by the troika, nor is he raising the minimum wage and increasing public sector salaries willy nilly. The truth is he doesn't really need them anymore, it's kind of likely he'll win the next election easily, grabbing the center and taking advantage of the currently uninspiring center-right leaders. Hell, I might even vote for him and I've never voted for non-center right parties.
TheDwf
Profile Joined November 2011
France19747 Posts
April 14 2018 18:17 GMT
#21537
Pathetic Macron who follows Trump and irresponsibly drops useless bombs in Syria. And to say he had promised to bin the neoconservative line followed under Sarkozy and Hollande... Another lie.
IgnE
Profile Joined November 2010
United States7681 Posts
Last Edited: 2018-04-14 18:59:36
April 14 2018 18:59 GMT
#21538
On April 13 2018 20:02 warding wrote:
That's spot on. António Costa is both an extremely lucky man and a very savvy politician. After Durão Barroso and Guterres, it's not difficult to see him taking a high-profile role in an international institution next.

I was super pissed when he maneuvered in 2015 to form an agreement with the extreme left loons after he finished 2nd in the election. What happened after that was genius: he basically kept the course that the previous center-right government had taken, reaping the benefits of the economic expansion while continuing to cut down the deficit (AKA AUSTERITY). The right is happy with public policy and the center-left is happy because it's in power and they somehow think 'austerity is over'.

Now the extreme left are pissed because António Costa isn't bringing down the labor reforms imposed by the troika, nor is he raising the minimum wage and increasing public sector salaries willy nilly. The truth is he doesn't really need them anymore, it's kind of likely he'll win the next election easily, grabbing the center and taking advantage of the currently uninspiring center-right leaders. Hell, I might even vote for him and I've never voted for non-center right parties.


To what extent is demography the real spectre behind European austerity policies?



This guy basically makes the point that only the US, among Western countries, has an upcoming Millennial generation to provide the raw demand for continued economic growth. Given that immigration, which could bring in younger (and more fertile?) people to provide European demand in the coming years, is such a political problem, maybe the economic strategists that dominate the ruling consensus in Europe are just trying to prevent a complete collapse?

Later on, Zeihan discusses European banking instability:

https://www.youtube.com/watch?v=feU7HT0x_qU#t=49m50s

calling Germany and Italy "terminal democracies," with Italy and Ireland, especially, have an enormous quantity of non-performing loans.
The unrealistic sound of these propositions is indicative, not of their utopian character, but of the strength of the forces which prevent their realization.
Nyxisto
Profile Joined August 2010
Germany6287 Posts
Last Edited: 2018-04-14 19:06:03
April 14 2018 19:04 GMT
#21539
It seems fairly reductionistic to reduce austerity to demographics, but even if you did the logic is basically the wrong way around. Very old societies should, if that were the only motivator, be extremely spending happy because old people have little reason to save and invest, because they have less time getting something out of their investments, whereas investment and delaying consumption ought to pay off for young societies.

That's not really the reason for austerity anyway. Austerity is popular in Germany especially because we're an export driven, risk-averse country with an economy that exports globally instead of consuming on the domestic market. In this sense Germany is like any other country with, low-debt, low-consumption politics like Singapore or China. Has nothing to do with demographics. It's also no big deal in terms of growth. Because we're not especially reliant on domestic consumption growth, having an aging population isn't really a problem.
IgnE
Profile Joined November 2010
United States7681 Posts
Last Edited: 2018-04-14 22:26:07
April 14 2018 22:20 GMT
#21540
I'm not really sure you've addressed the main point of the video above, which was that younger demographics are, empirically speaking, the ones that drive demand. Germany also largely sets policy for the entire eurozone. Who are its major trading partners? German export growth is financed in significant measure by other European lending, denominated in Euros, is it not? China itself, as a consequence of one-child policy, has similarly moribund demographic trends which simply cannot be reversed more quickly than a few decades. It takes time for babies to grow into consuming 20-somethings. The euro itself ties together these Italian, Spanish, and Irish economies, all with under-performing loans that only stand to get worse given the demographic changes. Tell me why the state of Italian bank loans is not something that should concern Germany.

I am not "reducing" austerity to demographics, but I am suggesting that if Eurozone economists and leaders believe Zeihan's basic assumptions, then austerity measures, including reducing spending and restricting bank lending, would be rational courses of action to prepare for an inevitable downward trend in demand for the foreseeable future. There seems to be a clear tension between demographic changes in Europe (including all the turmoil around immigration) depressing demand and debt-financed economic growth (if we can even call it "growth") that increasingly looks as if it might not ever be paid back. It is unclear to me if you fundamentally disagree with the assumption that younger people are foundational to demand, because I don't even know what to make of this "very old societies […] should should be extremely spending happy." Is this an empirical assertion on your part or just a hypothetical? Very old societies are also non-working societies. They pull their investments back to pay for things, but only because they don't have the income they did during mid-life. So very old societies have no tax base, no capital for investment, and insufficient demand. Right now, according to the figures Zeihan presents, much of Europe still has a sizable middle-aged population that provides the first two, at least in "healthy" economies like Germany, with a diminishing demand that looks to only get worse.
The unrealistic sound of these propositions is indicative, not of their utopian character, but of the strength of the forces which prevent their realization.
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