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Active: 480 users

First Chimera Monkeys - Page 3

Forum Index > General Forum
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NOobToss
Profile Joined October 2010
United States92 Posts
Last Edited: 2012-01-06 17:11:25
January 06 2012 17:09 GMT
#41
chimeras are produced routinely in mice when people want to breed mouse knockouts. t the only advance is that this could be done in primates, which frankly is minuscule.

the next obvious step that REALLY would have widespread implications would be to make inter-species chimeras, such as human-primate chimeras using human and primate ES cells, since we are related to them. but, that in itself would be VERY VERY controversial, that i don't really see it happening.


however i don't think there will be widespread genetic knockout studies done in primates in the near future because the cost of primate upkeep and adhering to institutional regulations regarding animal ethics and treatment will be prohibitively expensive.
FallDownMarigold
Profile Blog Joined December 2010
United States3710 Posts
Last Edited: 2012-01-06 17:11:55
January 06 2012 17:11 GMT
#42
On January 07 2012 02:09 NOobToss wrote:
chimeras are produced routinely in mice when people want to breed mouse knockouts. they do this by injecting the only advance is that this could be done in primates, which frankly is minuscule.

the next obvious step that REALLY would have widespread implications would be to make inter-species chimeras, such as human-primate chimeras using human and primate ES cells, since we are related to them. but, that in itself would be VERY VERY controversial, that i don't really see it happening.


however i don't think there will be widespread genetic knockout studies done in primates in the near future because the cost of primate upkeep and adhering to institutional regulations regarding animal ethics and treatment will be prohibitively expensive.


re: avian studies, chick-quail chimerics
NOobToss
Profile Joined October 2010
United States92 Posts
January 06 2012 17:13 GMT
#43
On January 07 2012 02:11 FallDownMarigold wrote:
Show nested quote +
On January 07 2012 02:09 NOobToss wrote:
chimeras are produced routinely in mice when people want to breed mouse knockouts. the only advance is that this could be done in primates, which frankly is minuscule.

the next obvious step that REALLY would have widespread implications would be to make inter-species chimeras, such as human-primate chimeras using human and primate ES cells, since we are related to them. but, that in itself would be VERY VERY controversial, that i don't really see it happening.


however i don't think there will be widespread genetic knockout studies done in primates in the near future because the cost of primate upkeep and adhering to institutional regulations regarding animal ethics and treatment will be prohibitively expensive.


re: avian studies, chick-quail chimerics



gotcha. i'm frankly uncomfortable with primate-human chimeras tbh.
FallDownMarigold
Profile Blog Joined December 2010
United States3710 Posts
January 06 2012 17:16 GMT
#44
On January 07 2012 02:13 NOobToss wrote:
Show nested quote +
On January 07 2012 02:11 FallDownMarigold wrote:
On January 07 2012 02:09 NOobToss wrote:
chimeras are produced routinely in mice when people want to breed mouse knockouts. the only advance is that this could be done in primates, which frankly is minuscule.

the next obvious step that REALLY would have widespread implications would be to make inter-species chimeras, such as human-primate chimeras using human and primate ES cells, since we are related to them. but, that in itself would be VERY VERY controversial, that i don't really see it happening.


however i don't think there will be widespread genetic knockout studies done in primates in the near future because the cost of primate upkeep and adhering to institutional regulations regarding animal ethics and treatment will be prohibitively expensive.


re: avian studies, chick-quail chimerics



gotcha. i'm frankly uncomfortable with primate-human chimeras tbh.


Yep, I don't see much use for that right now tho anyway =)

I think if anything it'd be a good proof of concept experiment, but I can't think of any particular advantages that could be gained from a human-primate chimera that couldn't be gained from other simpler chimeras
Disarm22
Profile Joined January 2011
United States151 Posts
January 06 2012 17:33 GMT
#45
this is disturbing. i wonder what creatures man will create next.
Cliiiiiiide!
Erik.TheRed
Profile Blog Joined May 2010
United States1655 Posts
January 06 2012 17:36 GMT
#46
someone found a philosopher's stone?
"See you space cowboy"
Taekwon
Profile Joined May 2010
United States8155 Posts
January 06 2012 17:38 GMT
#47
We can now make the perfect monkey warrior!
▲ ▲ ▲
Coal
Profile Joined July 2011
Sweden1535 Posts
January 06 2012 17:45 GMT
#48
MANBEARPIG!!! HALF MAN, HALF BEAR, HALF PIG, WE ARE ALL DOOMED!!!
In order to succeed, your desire for success should be greater than your fear of failure.
Atheist
Profile Joined December 2011
186 Posts
January 06 2012 17:47 GMT
#49
We honestly don't need God in the universe.
The more humanity increases its knowledge, the less relevant God becomes.
HellRoxYa
Profile Joined September 2010
Sweden1614 Posts
January 06 2012 17:51 GMT
#50
On January 06 2012 19:21 HaruRH wrote:
This discovery is very scary. One day, they might be able to start combining genomes of humans, resulting in superhumans...


Which isn't scary but absolutely awesome.
Tacky
Profile Joined July 2010
Sweden21 Posts
January 06 2012 17:51 GMT
#51
It's common to use chimeric mice in science, linking your wanted modified genetic trait to, for example, a gene causing brown fur and inserting in a white-mouse embryo creates a white/black spotted chimeric mouse allowing to know that you've successfully introduced new genes.

This is cool cause it's done on monkeys, it's hard to manipulate mammalian and in particular primate embryos.
frequency
Profile Blog Joined February 2010
Australia1901 Posts
January 06 2012 17:54 GMT
#52
When can we make a manbearpig?
www.twitter.com/marconofrio | marconofrio.tumblr.com
exShikari
Profile Joined December 2010
Australia237 Posts
January 06 2012 18:34 GMT
#53
This seems to be on the same scale as mules and sheep/goat hybrids...until we see a chimera produced from significantly different genomes this doesn't really warrant headline news.
It is, in the end, whatever the Hell I want it to be, And when I'm through with it, it's gonna blow a hole, This wide, straight through the worlds own idea of itself. They're throwing bottles at your house. Come on, lets go break their arms.
Krikkitone
Profile Joined April 2009
United States1451 Posts
Last Edited: 2012-01-06 18:41:29
January 06 2012 18:40 GMT
#54
A good bit of ignorance here

Chimera=/=hybrid

In a hybrid, Every single cell in the organism has the exact same genes from both parents (with the parents being of different species).

In a chimera, Some cells in the organism have one set of genes, and other cells (in other parts of the body) have other sets of genes.

So what the scientists did is they got 6 monkey embryos of the same species, and merged the Embryos. So when you get the adult, some parts of the body will have the genes from one embryo, and some from others.

This happens to some degree naturally. You have a few cells in you that have your mother's genes (picked up while you were in the womb, and were able to survive) Your mother has a few cells in her that have your genes, picked up while she was pregnant.


This is not Genetic engineering/combining genomes/ etc.
FallDownMarigold
Profile Blog Joined December 2010
United States3710 Posts
Last Edited: 2012-01-06 18:48:36
January 06 2012 18:42 GMT
#55
On January 07 2012 03:40 Krikkitone wrote:
You have a few cells in you that have your mother's genes (picked up while you were in the womb, and were able to survive) Your mother has a few cells in her that have your genes, picked up while she was pregnant.


What the fuck? Am I the only one that is missing something here, or is this dude completely wrong? What do you mean we have foreign cells from our moms with distinct genomes, inside our bodies? Where are they? Are they functional contributors to anything? In which regions do they grow, or survive? How do they survive? Do they have a stem cell population that replenishes them? Why don't they die off? Are they located in a niche in which multipotent progenitors can be induced to exist at certain times?
Amaterasu1234
Profile Joined November 2010
United States317 Posts
January 06 2012 18:53 GMT
#56
On January 06 2012 17:55 morninglightmountain wrote:
Pffft, TL had this figured out ages ago.

+ Show Spoiler +
[image loading]


I'm not really sure what the use of this is tbh, they say it has 'huge implications for science' and then don't elaborate. I bet i'm not going to benefit from this in my lifetime for sure...


Bringing back saber-toothed tigers! 'Cause that'd be sick!
iamahydralisk
Profile Blog Joined May 2010
United States813 Posts
January 06 2012 18:59 GMT
#57
I guess I've played way too many vidya games cause I came into this thread expecting some sort of three-headed monster monkeys who could breathe fire and shit
"well if youre looking for long term, go safe, if you expect it to end either way, go risky. wow. just like sc2" - friend of mine when I asked him which girl to pick
Humanfails
Profile Blog Joined November 2011
224 Posts
Last Edited: 2012-01-06 19:01:15
January 06 2012 19:00 GMT
#58
On January 06 2012 17:37 gosuMalicE wrote:
Show nested quote +
On January 06 2012 17:32 Chaosvuistje wrote:
Amazing, imagine all the possibilities! If I had the power to unethically forge creatures together I would definitely get a bird with 4 heads just so they never stop chirping.

It's good advancement, but we'll have to ask the question of how ethical this is every step of the way.

How could this be unethical they are animals, unless they stared doing it to humans, which I highly doubt will happen.



you're an animal too. To claim you are not is a fallacy religion has pushed since the beginning of time.

Animals feel pain.
animals have brains.

you have a brain (presumably).
you feel pain.

ethics derives from concepts of right and wrong.
Xalorian
Profile Joined September 2011
Canada433 Posts
January 06 2012 19:11 GMT
#59
So basically, if we could do that to a human, if all the embryo would be from different parents, the kid would have 6 fathers and 6 mothers, all biological.

Fucked up.

So many gift at christmas, tho.
darkscream
Profile Blog Joined December 2010
Canada2310 Posts
January 06 2012 19:26 GMT
#60
This is not great like so many people have said. The utmost care must be used regarding chimeras, because if they ever escape into the real world and ecosystem it could cause serious problems. However as long as its limited to a lab it certainly is a great opportunity... but often if these labs screw up or let stuff out we never hear about it, and in the case of genetic manipulation there's real danger in letting that happen.
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