EPTCan anyone here who knows more about this stuff suggest some sort of potential topics, because I've got about 0 idea what to write on and I want to get this done with as soon as I can.
Thanks~
[H] biochemistry topic
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Xeris
Iran17695 Posts
Can anyone here who knows more about this stuff suggest some sort of potential topics, because I've got about 0 idea what to write on and I want to get this done with as soon as I can. Thanks~ | ||
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radar14
United States1437 Posts
I'm not sure if it falls under "biochemistry" per se but a paper about anticoagulation treatments would be pretty interesting and not too hard imo. I remember writing a paper about coagulation (blood clotting factors) for one of my biochem lab classes. You could talk about the use of heparin (acute) and warfarrin (chronic) as anticoagulation therapies for heart attacks and other hypercoagulable states. Tying in warfarrin as a vitamin K antagonist would allow you to explore the physiology of the clotting cascade. Other things you could tie in peripherally: indications for the use of aspirin (antiplatelet), newer types of low-molecular weight heparin, the differences between primary and secondary clotting. Other ideas...cyanide poisoning/carbon monoxide/methhemoglobinemias and their treatments. Pretty easy, some standard redox stuff and electron transport chain, with some O2 binding curve stuff. Another good topic (but would probably require a decent amount of work) would be how being diabetic affects your metabolism i.e. shift to ketone body metabolism, becoming acidotic, lack of insulin increasing glycogenolysis and gluconeogesis, osmotic diuresis, etc. The physiology of hyperlipidemia; you can talk about how fatty acid synthesis relates to the cholesterols, how hyperlipidemia becomes a risk for athersclerosis, genetic risk factors for hyperlipidemia, and treatments (HMG-coa reducatase inhibitors and others) | ||
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fanatacist
10319 Posts
Marijuana. Lots of debate on this issue, so pretty hard to be entirely wrong. | ||
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Yizuo
Germany1537 Posts
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eshlow
United States5210 Posts
Biochemistry is so broad because it includes ALL systems of the body with everything that occurs on a molecular level. Pretty much anything that affects you can be "done" in biochemistry.... nutrition sports/performance/exercise sleep & sleep deprivation diseases/poisons & treatment drugs Or you could pick something that affects various organ systems or organs. brain/CNS, respiratory/lungs, digestive (and all its various organs), urinary (kidneys), etc. Just pick something that you're interested in that affects humans, and it probably has some biochemistry with it. Can't really go wrong with alcohol presentation especially in the college setting. :p BTW, what's your major? Like general biology or something? | ||
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GrayArea
United States872 Posts
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Xeris
Iran17695 Posts
On April 01 2009 01:54 eshlow wrote: Dude, it really depends what you're looking for... Biochemistry is so broad because it includes ALL systems of the body with everything that occurs on a molecular level. Pretty much anything that affects you can be "done" in biochemistry.... nutrition sports/performance/exercise sleep & sleep deprivation diseases/poisons & treatment drugs Or you could pick something that affects various organ systems or organs. brain/CNS, respiratory/lungs, digestive (and all its various organs), urinary (kidneys), etc. Just pick something that you're interested in that affects humans, and it probably has some biochemistry with it. Can't really go wrong with alcohol presentation especially in the college setting. :p BTW, what's your major? Like general biology or something? I'm a political science major. UCSD has 6 different colleges, and each has different GE requirements. I happened to get accepted into the "math/science" college, so I had to take: 2 bio, 3 chem, 1 physics, 3 calc classes. Biochem is my final chem class. So I have no clue about any of this stuff really =D The report has to be 5 pages, and I'm not sure about the presentation. | ||
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Xeris
Iran17695 Posts
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Hammy
France828 Posts
I did a short presentation on the GFP (green fluorescent protein) last semester for example. | ||
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miseiler
United States1389 Posts
On April 01 2009 03:01 GrayArea wrote: Pick an enzyme of your choice that is related to a common disease (i.e. acetylcholinesterase with relation to Alzheimer's Disease). Then, read papers on drug design projects that use enzyme kinetics in order to study the efficacy of potential drug inhibitors. Make an analysis of why certain drugs bind better than others based on analysis of the efficacy of the drug, the structure of the enzyme, and the ADMET (absorption, distribution, metabolism, excretion, and toxicity effects) of the drug. (e.g. you can show that maybe some study found that the designed compound interacts with the Serine residue in the catalytic triad of the active site gorge which is a form of competitive inhibition, etc. etc.) Show some michaelis-menten plots, some pictures of the column chromatography used to isolate the enzyme, get some pictures of the enzyme from the PDB, and that is your way to a perfect A+. Good Luck =) This. If you're at all interested in any drug pharma-related subject (ie, metabolism, toxicology, kinetics, even computer-aided design and to a lesser extent structural pharmacology etc), this is also a great place to start. Also, I used to work at the PDB. Not my cup of tea. Great research tool, though  | ||
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Archaic
United States4024 Posts
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Jayme
United States5866 Posts
On April 01 2009 03:09 Xeris wrote: I'm a political science major. UCSD has 6 different colleges, and each has different GE requirements. I happened to get accepted into the "math/science" college, so I had to take: 2 bio, 3 chem, 1 physics, 3 calc classes. Biochem is my final chem class. So I have no clue about any of this stuff really =D The report has to be 5 pages, and I'm not sure about the presentation. Only five pages? That's about uh 1,500 words... a joke in short. You can pick just about ANY biochem topic and hit 1,500 words easily. Easy topics will focus on specific enzymes and how they operate, how you block them etc etc. The topic is broad, anything from AIDS and it's treatments to cancer treatments how cancer forms... there is really no limit. | ||
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Xeris
Iran17695 Posts
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xhuwin
United States476 Posts
On April 01 2009 04:00 miseiler wrote: This. If you're at all interested in any drug pharma-related subject (ie, metabolism, toxicology, kinetics, even computer-aided design and to a lesser extent structural pharmacology etc), this is also a great place to start. Also, I used to work at the PDB. Not my cup of tea. Great research tool, though Ah I spent my junior year two summers ago doing bioinformatics research. We used the PDB pretty extensively at PIR in Georgetown. Pretty cool stuff! Good luck with your project. I don't know too many advanced biochem topics. | ||
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